Noun | 1. | histamine blocker - a medicine used to treat the gastric effects of histamine in cases of peptic ulcers and gastritis and gastroesophageal reflux; works by blocking the effects of histamine on the receptor site known as H2 cimetidine, Tagamet - a drug (trade name Tagamet) used to treat peptic ulcers by decreasing the secretion of stomach acid famotidine, Pepcid - a histamine blocker (trade name Pepcid) used to treat peptic ulcers and gastritis and esophageal reflux medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease ranitidine, Zantac - a histamine blocker and antacid (trade name Zantac) used to treat peptic ulcers and gastritis and esophageal reflux |