im·mu·no·sup·pres·sion

(ĭm′yə-nō-sə-prĕsh′ən, ĭ-myo͞o′-)

Suppression of the immune response, as by drugs or radiation, in order to prevent the rejection of grafts or transplants or to control autoimmune diseases. Also called immunodepression.

im′mu·no·sup·pres′sant (-prĕs′ənt) n.

im′mu·no·sup·pressed′ (-prĕst′) adj.

im′mu·no·sup·pres′sive adj.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

immunosuppression

(ˌɪmjʊnəʊsəˈprɛʃən)

(Medicine) medical suppression of the body's immune system, esp in order to reduce the likelihood of rejection of a transplanted organ

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

im•mu•no•sup•pres•sion

(ˌɪm yə noʊ səˈprɛʃ ən, ɪˌmyu-)

n.

the inhibition of the normal immune response because of disease, the administration of drugs, or surgery.

[1960–65]

im`mu•no•sup•press′, v.t. -pressed, -press•ing.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

immunosuppression - lowering the body's normal immune response to invasion by foreign substances; can be deliberate (as in lowering the immune response to prevent rejection of a transplanted organ) or incidental (as a side effect of radiotherapy or chemotherapy for cancer)

immunological disorder - a disorder of the immune system

Translations

ανοσοκαταστολή

immunosuppression

[ɪˈmjʊːnəʊsəˈpreʃən] N → inmunosupresión f

Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

immunosuppression

n inmunosupresión f

Mentioned in

References in periodicals archive

8, 2019 (HealthDay News) -- About two-thirds of patients who survive hospitalization for sepsis have persistent elevation of inflammation and immunosuppression biomarkers, which is linked to increased mortality, according to a study published online Aug.

Persistent Inflammation After Sepsis Linked to Higher Mortality; Persistent inflammation, immunosuppression linked to increased mortality and readmission after discharge

OKARA -- A young man has been suffering from a rare disease called immunosuppression, as per his pathological reports and CT-Scan views from various diagnostic labs.

Family seeks support for young man's treatment

In pre-clinical studies, SC-islets were delivered into diabetic non-human primates under immunosuppression. SC-islets were infused into the portal vein to mimic planned human clinical trials.

Semma Therapeutics Announces Pre-Clinical Proof-of-Concept in Two Lead Programs in Type 1 Diabetes

"Demodicosis can be associated with immunosuppression. Kids with Langerhans cell histiocytosis seem to be prone to it.

Rhymin' pediatric dermatologist provides Demodex tips

Clinical data have shown the potential for FCR001 to durably free a significant proportion of living donor kidney transplant recipients from all chronic immunosuppression by 12 months after their transplant, without rejection of their transplanted organ.

Talaris Therapeutics Reports Promising Phase 2 Data of Novel, Allogeneic Cell Therapy in Living Donor Kidney Transplant Recipients

Preclinical studies showed that treatment with ReLiver allows to effectively replace liver functions, decreasing mortality by three times, preventing and treating hepatic encephalopathy, and promoting liver regeneration, without the need of immunosuppression.

Morphocell Obtains License To Commercialize Encapsulated Liver Tissue Technology: University of Montreal Scientists Derive Liver Tissue From Stem Cells

Healthcare company Sanofi (EURONEXT:SAN) (NASDAQ:SNY) reported on Wednesday the receipt of approval from the US Food and Drug Administration (FDA) for Cablivi (caplacizumab-yhdp) in combination with plasma exchange and immunosuppression for the treatment of acquired thrombotic thrombocytopenic purpura (aTTP) in adults.

Sanofi wins US FDA approval for Cablivi for treating acquired thrombotic thrombocytopenic purpura

Food and Drug has approved Cablivi (caplacizumab-yhdp) in combination with plasma exchange and immunosuppression for the treatment of acquired thrombotic thrombocytopenic purpura (aTTP) a rare blood disorder in adults.

FDA approves Sanofi's Cablivi for adults with a rare blood disorder

Food and Drug Administration has approved Cablivi in combination with plasma exchange and immunosuppression for the treatment of acquired thrombotic thrombocytopenic purpura in adults.

Sanofi says FDA approves Cablivi for adults with aTTP

However, the outcomes and effects of donations from live and deceased donors are yet to be compared, and the surgical and immunosuppression techniques will be optimised in the future.

Baby Born: Uterus Transplant from Deceased Donor

But high rejection rates and life-threatening complications from immunosuppression have limited the success of human intestinal transplantation.

Blood-Forming Stems Cells Found In A Surprising Location: The Human Gut

To the Editor: Regulatory T-cells (Tregs), a subset of CD4+ T-cells, have the capacity to actively suppress immune responses and play a pivotal role in sepsis-induced immunosuppression.[1] B- and T-lymphocyte attenuator (BTLA) is a co-inhibitory receptor that is known to potently inhibit CD4+ T-cell function and to block prosurvival signaling in CD4+ T-cells.[2] Tregs constitutively express BTLA.

B- and T-Lymphocyte Attenuator Expression on Regulatory T-Cells in Patients with Severe Sepsis