in·ter·leu·kin

(ĭn′tər-lo͞o′kĭn)

Any of various small proteins that are produced by a variety of cell types, especially T cells and other white blood cells, and that regulate many aspects of inflammation and the immune response, including stimulating the production of white blood cells and platelets.

[inter- + leuk(o)- + -in.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

interleukin

(ˌɪntəˈluːkɪn)

(Biochemistry) a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

in•ter•leu•kin

(ˈɪn tərˌlu kɪn)
n.

any of a family of small proteins that participate in the body's defense system, esp. by promoting the growth and activation of white blood cells.

[1979; inter- + leuk (ocyte) + -in¹; so called because such proteins act as agents of communication between different populations of leukocytes]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system

lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)

Mentioned in

References in periodicals archive

Kaski, "Serum levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina," Circulation, vol.

Fungal exposure and low levels of IL-10 in patients with sarcoidosis

Bignotti et al., "Increased serum interleukin-8 and interleukin-10 in schizophrenic patients resistant to treatment with neuroleptics and the stimulatory effects of clozapine on serum leukemia inhibitory factor receptor," Schizophrenia Research, vol.

Cryoglobulins as potential triggers of inflammation in schizophrenia

The researchers, from Brigham and Women's Hospital, and Harvard Stem Cell Institute, and collaborators at MIT and Massachusetts General Hospital, inserted modified strands of messenger RNA into connective tissue stem cells--called mesenchymal stem cells--which stimulated the cells to produce adhesive surface proteins and secrete interleukin-10, an anti-inflammatory molecule.

Stem cells engineered to become targeted drug factories

The researchers, from Brigham and Women's Hospital, and Harvard Stem Cell Institute, and collaborators at MIT and Massachusetts General Hospital, inserted modified strands of messenger RNA into connective tissue stem cells --called mesenchymal stem cells--which stimulated the cells to produce adhesive surface proteins and secrete interleukin-10, an anti-inflammatory molecule.

Stem cells engineered to become targeted drug factories

Interleukin-10 predicts preterm birth in acculturated Hispanics.

"Hispanic Paradox" and Irish preterm birth data

Interleukin-10 (IL-10) is a potent pleiotropic cytokine, located on chromosome 1q31-32, consisting of five exons and four introns.

Evaluation of interleukin-10 (G-1082A) promoter polymorphism in preeclampsia

Forrester, "Secretion of interleukin-10 or interleukin-12 by LPS-activated dendritic cells is critically dependent on time of stimulus relative to initiation of purified DC culture," Journal of Leukocyte Biology, vol.

An Fc gamma receptor-mediated upregulation of the production of interleukin 10 by intravenous immunoglobulin in bone-marrow-derived mouse dendritic cells stimulated with lipopolysaccharide in vitro

Robert et al., "Serum profiles of interleukin-6, interleukin-8, and interleukin-10 in patients with severe and mild acute pancreatitis," Pancreas, vol.

The role of IL-6, 8, and 10, STNFR, CRP, and pancreatic elastase in the prediction of systemic complications in patients with acute pancreatitis

Compared with bupivacaine alone, bupivacaine plus ketorolac was associated with lower levels of interleukin-6 (P = .012) and interleukin-10 (P = .004) in wound exudate.

Drug combination improved local analgesia after cesarean

(5) Rook notes that the observed relationship between abundant Acinetobacter and increased expression of interleukin-10 suggests that Hanski's team has documented a genuine case of immunoregulation by environmental bacteria.

Reduced bacterial biodiversity is associated with increased allergy

Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression.

Acute respiratory failure from pulmonary tuberculosis due to head trauma immunosupression