interleukin

Also found in: Medical, Encyclopedia.
(redirected from Interleukin-11)

in·ter·leu·kin

 (ĭn′tər-lo͞o′kĭn)
n.
Any of various small proteins that are produced by a variety of cell types, especially T cells and other white blood cells, and that regulate many aspects of inflammation and the immune response, including stimulating the production of white blood cells and platelets.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

interleukin

(ˌɪntəˈluːkɪn)
n
(Biochemistry) a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

in•ter•leu•kin

(ˈɪn tərˌlu kɪn)
n.
any of a family of small proteins that participate in the body's defense system, esp. by promoting the growth and activation of white blood cells.
[1979; inter- + leuk (ocyte) + -in1; so called because such proteins act as agents of communication between different populations of leukocytes]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Mentioned in
References in periodicals archive
According to the company, BBT-059 is a proprietary, long-acting interleukin-11 analog that stimulates production of platelets, a type of blood cell important for blood clotting.
Williams, "Interleukin-11: review of molecular, cell biology, and clinical use," Blood, vol.
Kong, "Interleukin-11 protects mouse liver from warm ischemia/reperfusion (WI/Rp) injury," Clinics and Research in Hepatology and Gastroenterology, vol.
Dorner, "Hematopoietic, immunomodulatory and epithelial effects of interleukin-11," Leukemia, vol.
Interleukin-1 beta (IL-1b) and TNF-a stimulate the expression and release of interleukin-6 (IL-6), leukemia inhibitory factor and Interleukin-11 (IL-11) in human gingival fibroblasts.
Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells.
Interleukin-11 (IL-11) is a multifunctional cytokine essential in the differentiation and function of osteoclasts 24, 25 and IL-11 and its receptor are possible pathogenic factors in conditions associated with bone loss [26, 27].
Interleukin-11 therapy selectively down regulates type I cytokine proinflammatory pathways in psoriasis lesions.
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.