The most commonly reported ocular adverse reactions that occurred in patients treated with DEXTENZA were anterior chamber inflammation including iritis and
iridocyclitis (10%) and elevations in intraocular pressure (6%).
The most common ocular adverse reactions in subjects treated with Dextenza were: anterior chamber inflammation including iritis and
iridocyclitis, increased intraocular pressure, reduced visual acuity, cystoid macular edema, corneal edema, eye pain, and conjunctival hyperemia.
Acthar Gel is FDA-approved for the treatment of severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa such as: keratitis, iritis,
iridocyclitis, diffuse posterior uveitis and choroiditis, optic neuritis, chorioretinitis and anterior segment inflammation.
* Eye changes--superciliary and ciliary madarosis, superficial punctate keratitis, iris pearls, iritis,
iridocyclitis, secondary cataracts, glaucoma, cranial nerve palsies occur in the later stages.
Some non-specific symptoms can occur, but they are less frequent, including anorexia, headache, dizziness, cough, sore throat, loose bowels, nausea, vomiting, retinal abnormalities, hypertensive
iridocyclitis, and retro-orbital pain.
Rubella virus as a possible etiological agent of Fuchs heterochromic
iridocyclitis. Graefes Arch Clin Exp Ophthalmol.
An electronic search was performed for patients visiting Cleveland Clinic between January 2005 and January 2016 with the International Classification of Diseases (ICD)-9 and 10 codes for HS (705.83) and IED (scleritis, uveitis,
iridocyclitis, iritis, keratitis, and conjunctivitis).
Anterior segment signs included conjunctival chemosis (2 eyes, Figure 1), conjunctival and episcleral congestion (6 eyes), corneal edema (1 eye), corneal epithelium erosion (1 eye),
iridocyclitis (3 eyes), rubeosis iridis (11 eyes, Figure 2(a)), neovascular glaucoma (7 eyes), sluggish light reflex (13 eyes), and asymmetric cataract (10 eyes).
The common eye complications observed in leprosy include lagophthalmos, impaired corneal sensation, exposure keratopathy, corneal ulceration, corneal opacity, cataract,
iridocyclitis, ectropion, entropion, trichiasis, secondary glaucoma, iris atrophy and chronic dacryocystitis.
The frequency of JIA-associated anterior non-granulomatous uveitis (
iridocyclitis) is reported as being 15-67% in various European regions (34).