factor V

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(redirected from labile factor)
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Noun1.factor V - a coagulation factorfactor V - a coagulation factor      
accelerator factor, proaccelerin, prothrombin accelerator
clotting factor, coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation
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References in periodicals archive
The first gain-of-function mutation associated with venous thrombosis [the G1691A substitution in the F5 [3] gene, coagulation factor V (proaccelerin, labile factor)] was also found by studying an abnormal plasma phenotype (resistance to activated protein C).
A novel genetic risk factor for venous thrombosis
Multiplex genotyping for the [F5.sup.1] [coagulation factor V (proaccelerin, labile factor)] Leiden (1691G>A), F2 [coagulation factor II (thrombin)] 20210G > A, and MTHFR [methylenetetrahy drofolate reductase (NAD(P)H)] 1298A > C and 677C > T thrombophilia mutations distinguishes up to 81 ([3.sup.4]) combinations in solution without physical processing (1).
Detecting rare thrombophilia variants by high-resolution melting
Single-base variants, such as the F5 [coagulation factor V (proaccelerin, labile factor)] Leiden variant, were genotyped by melting hybridization probes (2), and in 2003 these tests became the first genetic tests cleared by the US Food and Drug Administration.
Making DNA melting useful
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