mac·ro·ceph·a·ly

(măk′rō-sĕf′ə-lē) also mac·ro·ce·pha·li·a (-sə-fā′lē-ə, -fāl′yə)

Abnormal largeness of the head. Also called megacephaly, megalocephaly.

mac′ro·ce·phal′ic (-sə-făl′ĭk), mac′ro·ceph′a·lous adj.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

macrocephaly

(ˌmækrəʊˈsɛfəlɪ) or less commonly

macrocephalia

(Pathology) the condition of having an abnormally large head or skull

macrocephalic, ˌmacroˈcephalous adj

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

mac•ro•ceph•a•ly

(ˌmæk roʊˈsɛf ə li)
n.

disproportionate largeness of the skull or head.

[1885–90]

mac`ro•ce•phal′ic (-səˈfæl ɪk) adj.

macrocephalism, macrocephaly

a condition in which the head or cranial capacity is unusually large. — macrocephalic, macrocephalous, adj.

See also: Head

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

macrocephaly - an abnormally large head; differs from hydrocephalus because there is no increased intracranial pressure and the overgrowth is symmetrical

megacephaly, megalocephaly

abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies

Translations

macrocéphalie

macrocefalia

Mentioned in

References in periodicals archive

During physical examination, macrocephaly with the cephalic perimeter of 56 cm (>97 centile) and plagiocephaly, height of 149 cm (25 centile), weight of 49.3 kg (60 centile), three trichoglyphs on the scalp, a prominent metopic ridge, asymmetric and dysmorphic facial features (figure 1) with a high palate were observed.

Syndromic Intellectual Disability Caused by a Novel Truncating Variant in AHDC1: A Case Report

The case was assessed as BRRS based on the macrocephaly, lipomatous lesions and pigmented macular lesions on the penis.

Bannayan-Riley-Ruvalcaba Syndrome in a Case Evaluated Due to Multinodular Goiter

The patients may present with disproportionate short stature, macrocephaly, lumbar lordosis, rhizomelic and mesomelic shortness and brachydactyly (1,2).

Evaluation of Efficacy of Long-term Growth Hormone Therapy in Patients with Hypochondroplasia

(1) Older infants may present with macrocephaly, neurodevelopmental disorders and seizure.

Interhemispheric cyst with associated dysplasia of the corpus callosum

Left ventricular cardiomyopathy and macrocephaly can be observed, but not frequently (4).

3-Hydroxy-3-methylglutaryl-CoA (HMG-CoA) Lyase Deficiency

Autistic individuals present with brain overgrowth and macrocephaly, with individuals affected by Alzheimer's having physiologic decline in the weight of the brain and subsequent broadening of the lateral ventricles with increasing age (Skullerud, 1985; Sacco et al., 2015).

Rango de Referencia del Peso Cerebral Post-Mortem para una Poblacion Sudafricana Seleccionada

Majority of the children presented with macrocephaly while three presented with papilloedema and sixth nerve palsy.

An experience with ventriculoperitoneal shunting at keen's point for hydrocephalus

Representative features of achondroplasia include an average-sized trunk, short limbs and macrocephaly.

Understanding genetic risks to buffalo populations

Duplications or deletions at a genome region known as 1q21.1 are known to cause macrocephaly or microcephaly, respectively, and are associated with a range of neurodevelopmental disorders, including ADHD, autism spectrum disorder, and intellectual disability.

Meet NOTCH2NL, Human-Specific Genes That May Have Given Us Our Big Brains

In this case report, we present the case of a 4-year-old girl patient who presented with macrocephaly and was diagnosed with VGAM.

Vein of Galen Aneurysmal Malformation Presenting with Macrocephaly

The associated findings in BCNS, in addition to medulloblastoma, include macrocephaly and dysmorphic features such as cleft lip or palate, frontal bossing, and hypertelorism.

Dermatology pearls to consider in children with cancer