GIF

(gĭf, jĭf )

n. Computers

1. A raster-based format for storing files of color graphics.

2. An image or animated clip recorded in such a format.

[G(raphics) I(nterchange) F(ormat).]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

GIF

(ɡɪf)

(Computer Science)

a. a standard compressed file format used for pictures

b. a picture held in this format

[C20: from g(raphic) i(nterchange) f(ormat)]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

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References in periodicals archive

The article, "Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor," is the first publication reporting the potential clinical utility of MN-166 for GBM.

MediciNova publishes findings on MN-166 in glioblastoma

Macrophage migration inhibitory factor, TNF-[alpha], IL-1[beta], IL-6, and IL-8, and monocytes are in the peritoneal fluid of endometriosis patients (1).

It Is the Time to Treat Endometriosis Based on Pathophysiology

When investigating how exosomes exert their effects on liver cells, Lyden and his team found that pancreatic cancer exosomes contain a protein called macrophage migration inhibitory factor (MIF).

How Pancreatic Cancer Spreads to the Liver

Intracoronary ACS levels of cytokines (IL-1, IL-6, IL-8, IL-12, IL-17, TNF-[alpha], tissue plasminogen activator inhibitor (tPAI)-1, and macrophage migration inhibitory factor, MIF) are increased when compared with aortic blood [9,12,13].

MIF mRNA Expression and Soluble Levels in Acute Coronary Syndrome

McKeown et al., "Macrophage migration inhibitory factor induces macrophage recruitment via CC chemokine ligand 2," The Journal of Immunology, vol.

Serum Matrix Metalloproteinase 9 and Macrophage Migration Inhibitory Factor (MIF) Are Increased in Young Healthy Nonobese Subjects with Positive Family History of Type 2 Diabetes

Coeuru et al., "Protective role of macrophage migration inhibitory factor in nonalcoholic steatohepatitis," The FASEB Journal, vol.

The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications

According to the company, MN-166 (ibudilast) is a first-in-class, orally bioavailable, small molecule phosphodiesterase (PDE) -4 and -10 inhibitor and a macrophage migration inhibitory factor (MIF) inhibitor that suppresses pro-inflammatory cytokines and promotes neurotrophic factors.

MediciNova passes the European Commission's orphan medicinal product designation for MN-166 for amyotrophic lateral sclerosis (ALS)