Estimation of product of lipid peroxidation (
malonyl dialdehyde) in biochemical systems.
In most of the iridoids obtained from Plumeria species, a simple or branched alkyl chain of four carbons is introduced at C-10 by
malonyl CoA or acetyl CoA as ketide group which is then reduced to unsaturated or saturated alkyl chain or modified to lactonic moiety [22].
Bu amacla aescin ekstrakti karistirdiklari (100 mg/kg dozda) standart besin veya yuksek yagli besini 5 hafta boyunca verdikleri erkek sicanlarda doku ve kan orneklerini alarak oksidatif stres gostergeleri olan
malonyl dialdehid, redukte glutathion ve superoksid dismutaz ile katalaz miktarlarini olcmuslerdir.
Malonyl groups are condensed with acetyl-CoA, catalyzed by acyltransferase (ACP), followed by the sequential addition of 2 carbon units to extend the fatty acid chain [22].
A adiponectina eleva a sensibilidade a insulina nos tecidos ao ativar a via MAPK, a qual inibe a enzima Acetil CoA Carboxilase, que por sua vez reduz as concentracoes de
malonyl CoA e, consequentemente, provoca elevacao da beta oxidacao e reducao na lipogenese.
1995 Transferase Table 2 Lipogenic Enzymes Regulated by SREBP-1c Enzyme Abbreviation Fatty Acid Synthase FAS Acyl CoA Carboxylase ACC ATP Citrate Lyase ACL Stearoyl CoA Desaturase SCD Malic Enzyme ME Enzyme Function Fatty Acid Synthase Synthesizes fatty acids from acetyl coenzyme A (CoA) and palmitate Acyl CoA Carboxylase Synthesizes
malonyl CoA from acetyl CoA ATP Citrate Lyase Converts citrate and CoA to acetyl CoA Stearoyl CoA Desaturase Synthesizes unsaturated fatty acids (oleate) from saturated fatty acids (stearate) Malic Enzyme Generates reducing equivalents (NADPH) for triglyceride synthesis
A solution of
malonyl dichloride (1.0 mmol) in C[H.sub.2][Cl.sub.2] (20 mL) was dropped in the solution of 2,3-bis(benzyloxy)-N-(hydroxyalkyl)benzamide (2.0 mmol) and [Et.sub.3]N (2.0 mL) in C[H.sub.2][Cl.sub.2] (20 mL) under ice bath and vigorous stirring conditions.
The following flavonol derivatives were identified and evaluated quantitatively: rutin, hyperoside, isoquercitrin, quercetin
malonyl glucoside, quercitrin, isorhamnetin rutinoside, and isorhamnetin glucoside.
Comparative analysis of their expression levels at stage S1 and S2 showed that in both cases, acyl carrier protein (ACP) and stearoyl-ACP desaturase (SAD) were obviously up regulated (<2 fold at most), while pyruvate dehydrogenase complex (PDHC) and acetyl-CoA carboxylase (ACCase) involved in the initial synthesis exhibited much higher expression levels than those involved in elongation stage such as malonyl-CoA: ACP
malonyl transferase (MCMT) and ketoacyl-ACP synthase (KAS).
Resistomycin compound is composed of
malonyl and acetyl unit, both of which come under the category of acetogenins.
Many trials have used serum Magnesium level, (7) C-reactive protein levels, (8)
malonyl dialdehyde, (9) white blood cell count (9) as a predictor for mortality and morbidity following acute myocardial infarction and risk of developing adverse cardiac events like sudden cardiac death and congestive heart failure.