median lethal dose

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median lethal dose

or

mean lethal dose

n
1. (Medicine) the amount of a drug or other substance that, when administered to a group of experimental animals, will kill 50 per cent of the group in a specified time
2. (Medicine) the amount of ionizing radiation that will kill 50 per cent of a population in a specified time
Abbreviation: LD50
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

me′dian le′thal dose′


n.
the quantity of a lethal substance, as a poison or pathogen, or of ionizing radiation that will kill 50 percent of the organisms subjected to it in a specified time period. Symbol: LD50
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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References in periodicals archive
In a previous study (Ali et al., 2018a) four isolates of SpltNPV-Pak were found that were faster than SpltNPV-Pak-BNG, while having the same median lethal dose. It would be of interest now to determine whether these faster acting SpltNPVs further reduce the food uptake and hence further limit crop damage.
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The median lethal dose ([LD.sub.50]) was calculated by the Reed-Muench method.
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For perspective, the median lethal dose in humans of whole body ionizing radiation calculated from data based upon young adults inside reinforced concrete buildings that remained standing in Nagasaki after detonation of the atomic bomb in World War II is about 3 Gy.
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