A muscle disease, usually degenerative, but sometimes caused by drug side-effects, chemical poisoning, or by chronic disorder of the immune system. The muscles generally fail to function fully.
Testing for pompe disease, spinal muscular atrophy (SMA), and carnitine palmitoyltransferase deficiency (a metabolic myopathy), is recommended for newborns in the U.S.
This finding suggested a reason why the progression of disease over time in metabolic myopathy (including lipid storage myopathy) is not as severe as that in IIM but, instead, varies in duration.
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