leukodystrophy

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leukodystrophy

(ˌluːkəʊˈdɪstrəfɪ)
n, pl -phies
(Pathology) pathol any of several progressive disorders characterized by the degeneration of white matter or myelin
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References in periodicals archive
Acetobacter indonesiensis bacteremia in child with metachromatic leukodystrophy. Emerg Infect Dis.
Sessa, "Metachromatic leukodystrophy: an overview of current and prospective treatments," Bone Marrow Transplantation, vol.
Metachromatic leukodystrophy: a model for the study of psychosis.
Among the sedatives used for procedural sedation, IV pentobarbital, rectal methohexital and thiopental are the most extensively studied barbiturates.18 There are a few studies about the use of rectal thiopental and IV thiopental for paediatric MRIs in literature.7,19-22 In a prospective study about sedation for children with metachromatic leukodystrophy undergoing MRI, Mattioli et al.
It is categorised as predominant white matter involvement with a sub-category of predominant periventricular involvement which includes the four cases of Metachromatic Leukodystrophy. The other group with predominant deep gray matter involvement are two cases of Wilson's disease and two cases of Pantothenate Kinase deficiency.
When including the community, you need to make sure you include lots of voices in the community." Patricia Lang is a Minnesota representative of Region 4 Midwest Genetics Collaborative (a coalition made up of seven states who strive to better health care access and genetic services) and the mother of a 19 year-old daughter, named Maddie, with metachromatic leukodystrophy. Metachromatic leukodystrophy is a genetic progressive condition (involves a mutation of the ARSA--a gene) that leads to an accumulation of fatty substances in areas of the central and peripheral nervous systems.
Global Markets Direct's, 'Metachromatic Leukodystrophy (MLD) - Pipeline Review, H1 2016', provides an overview of the Metachromatic Leukodystrophy (MLD) pipeline landscape.
The MRI changes of the CCFDN patients were evaluated by a scoring system, previously used for metachromatic leukodystrophy [15], adapted for CCFDN patients, with a maximal result of 33 points, corresponding to the most severe changes (Table 1).
After 10 years of battling the disease, Joselyn, 12, died in February 2013 of metachromatic leukodystrophy, a fatal genetic disorder that attacks the nervous system and left the little girl bedridden.
In situations of genetically inherited diseases, bone marrow MSCs have also been used as a therapeutic for Hurler's syndrome and metachromatic leukodystrophy. After undergoing successful bone marrow transplantation from human leukocyte antigen (HLA) identical siblings, 11 patients suffering from metachromatic leukodystrophy were given bone marrow MSCs from their sibling donors by injection.
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