min·o·cy·cline

(mĭn′ə-sī′klēn′, -klĭn)

A broad-spectrum antibiotic, C₂₃H₂₇N₃O₇, derived from tetracycline and used usually in the form of its hydrochloride.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

minocycline - tetracycline antibiotic (trade name Minocin) used to treat a variety of bacterial and rickettsial infections

Minocin

Achromycin, tetracycline - an antibiotic (trade name Achromycin) derived from microorganisms of the genus Streptomyces and used broadly to treat infections

Translations

minocycline

n minociclina

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References in periodicals archive

Deng's laboratory is conducting additional pre-clinical studies using the human-derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

"Support" cells in brain play important role in Down Syndrome

Four of the children had a history of receiving minocycline before hospitalization.

Characteristics of hospitalized children infected with macrolide-resistant Mycoplasma pneumoniae

In all studies other than the current one intermittent drainage was performed and drainage systems were used without leaving any residue.8914 It was reported that the risk of UTIs could be reduced with urinary catheters implanted for a short term and the use of antibiotics constituting a synergistic antimicrobial spectrum in silicone materials.15 It was demonstrated that the efficacy of antibiotic-coated silicones in the urinary system was only on the catheter and that it was not effective against planktonic (suspended) microorganisms.4 While Minocycline is a protein synthesis inhibitor Rifampin impacts the deoxyribonucleic acid (DNA)-associated ribonucleic acid (RNA) polymerase upon inhibiting it.

Evaluation of antimicrobial activities of minocycline and rifampin-impregnated silicone surfaces in an in vitro urinary system model

Systemic antibiotics, most commonly minocycline 100 mg twice daily for 30 days or doxycycline 100 mg twice daily for 30 days, are safe and effective for CRP.

Cutaneous eruption on chest and back: the cause of this "dirty" rash was fairly obvious to us, but only because we'd encountered this rare skin disorder before

Minocycline treatment for confluent & reticulate papilomatosis 1996, 57, 454-7.

Confluent and reticulate papillomatosis: a report of two cases

Treatment with the two antioxidants did not alter this pattern of activity; only the size of the peak in the evening was modified in the presence of minocycline and AA treated groups.

La minociclina, pero no el acido ascorbico, incrementa la actividad motora y extiende el periodo de vida de Drosophila melanogaster

Murray has ordered minocycline, a related tetracycline-class antibiotic, to replace doxycycline for the tick-borne ehrlichiosis and anaplasmosis that he commonly sees in southern Arizona, as well as for treating kennel cough.

Doxycycline shortage leaves people and pets scrambling for treatment alternatives: drug of choice for treating tick-borne disease and heartworm is unavailable (or unaffordable) due to supply bottleneck

One potential candidate medication is minocycline, particularly because of its ability to inhibit the expression of matrix metalloproteinases (MMPs).

Reducing haemorrhagic transformation after thrombolysis for stroke: a strategy utilising minocycline

Several studies have investigated the role of minocycline on inhibiting or altering microglial activation.

Microglial responses after ischemic stroke and intracerebral hemorrhage

They have also been able to show that the antibiotic minocycline inhibits the degradation and that treatment in adolescence can be linked to a reduced risk of developing schizophrenia.

Treatable mechanism identified in patients with schizophrenia

BioPharmX announced that the last patient in the company's Phase 2b clinical trial of BPX-041, a novel topical gel formulation of fully solubilized minocycline for the treatment of papulopustular rosacea, has completed their last clinical visit.

BioPharmX reports last patient visit in Phase 2b papulopustular rosacea trial