mi·to·gen

(mī′tə-jən)

An agent that induces mitosis.

mi′to·gen′ic (mī′tə-jĕn′ĭk, mĭt′ə-) adj.

mi′to·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

mitogen

(ˈmaɪtədʒən)

(Biology) any agent that induces mitosis

mitogenic, mitogenetic adj

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

mi•to•gen

(ˈmaɪ tə dʒən, -ˌdʒɛn)

n.

any substance or agent that stimulates mitosis.

[1950–55; mito (sis) + -gen]

mi`to•gen′ic (-ˈdʒɛn ɪk) adj.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

mitogen - an agent that triggers mitosis

agent - a substance that exerts some force or effect

Translations

mi·to·gen

n. mitógeno, sustancia que induce mitosis celular.

English-Spanish Medical Dictionary © Farlex 2012

Mentioned in

agent

References in periodicals archive

The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus.

Protective effects of asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice

18 January 2012 - German Wilex AG (ETR:WL6) said on Wednesday it had successfully completed a Phase I dose escalation trial with its oral Mitogen activated protein kinase (MEK) inhibitor WX-554 demonstrating activity, safety and tolerance in healthy volunteers.

Wilex finalises oral MEK inhibitor WX-554 Phase I trial

(Fabaceae) on mitogen response of the spleen cells in Graffi tumor bearing (GTBH) and healthy hamsters were reported.

Immunorestoration and augmentation of mitogen lymphocyte response in Graffi tumor bearing hamsters by purified saponin mixture from Astragalus corniculatus

The mitogen phytohemagglutinin is used as an assay control and saline as a negative control or "nil antigen." After incubation, the plasma is separated and the concentration of interferon-[gamma] measured by enzyme-linked immunosorbent assay.

CDC issues guidance for new latent tuberculosis test. (In High-Risk Patients)

In this group, social QoL was also negatively associated with %HLA-DR+ in T cells (r = -.245) and mitogen stimulated T cell function (IL2R expression on T cells after 72 h incubation with PHA; r = -.243).

33. Viscum album extract application and the correlation between quality of life and lymphocyte subpopulations in tumour patients

In addition to pregabalin, other promising investigational approaches include nerve growth factor blockade as well as the targeting of proinflammatory glial cells and cytokines such as p38 mitogen activated protein (MAP) kinase.

Pharmacologic progress in fibromyalgia care

The cells were incubated for 96h with both VA-E at 0, 10, 100 and 1000 [micro]g/ml, interleukin-6 at 1000 U/ml, and pokeweed mitogen and phytohaemagglutinine at 2.5 [micro]g/ml.

46. Decrease of in vitro susceptibility of B-CLL cells of patients treated with Viscum album extract towards the applied extract

The murine splenocytes were used to assess lymphocyte proliferation response after mitogen stimulating for 20h.

Antitumor and immunostimulating effects of Anoectochilus formosanus Hayata

The mitogen phytohemagglutinin is used as an assay control and saline as a negative control or "nil antigen." After incubation, the plasma is separated and the interferon-[gamma] level measured by enzyme-linked immunosorbent assay The QFT score is based on the proportion of interferon-[gamma] released in response to tuberculin, compared with phytohemagglutinin.

CDC issues guidance for latent tuberculosis test. (In High-Risk Patients)

The results obtained show that most of the extracts exerted inhibitory effect on tumor as well as on mitogen activated normal spleen cell growth.

Immunomodulating properties of Argentine plants with ethnomedicinal use

Such effects were mediated by local conversion of DHEA to estrogen, acting through the estrogen receptor, and vitro studies suggest a direct effect on specific pro-inflammatory cytokine production by macrophages via mitogen activated kinase (MAP) and phosphatidylinositol 3 (PI3) kinase pathways.

The sex steroid precursor DHEA accelerates cutaneous wound healing via the estrogen receptors