monokine

Also found in: Medical, Encyclopedia, Wikipedia.

monokine

(ˈmɒnəʊˈkaɪn)
n
(Physiology) a type of protein or cytokine that is developed from macrophagic or monocytic cells
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

mon•o•kine

(ˈmɒn əˌkaɪn)

n.
a substance that is secreted by monocytes or macrophages in the immune response and that affects the function of other cells.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive
To achieve this purpose, the impact of FR in mice receiving HFD or HCD during 56 days on serum levels of basic fibroblast growth factor (FGF-basic), granulocyte-macrophage colony-stimulating factor (GM-CSF), inducible protein 10 (IP-10), interferon [gamma] (IFN-[gamma]), interleukin 1[alpha] (IL-1[alpha]), IL-1[beta], IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-13, IL-17, keratinocyte chemoattractant (KC), macrophage inflammatory protein-1[alpha] (MIP-1-[alpha]), monocyte chemotactic protein 1 (MCP-1), monokine induced by IFN-[gamma] (MIG), and tumor necrosis factor [alpha] (TNF-[alpha]) were evaluated.
Citing unpublished data from a postmortem study of 24 brains, Sherry Ferguson, PhD, research psychologist at the FDA National Center for Toxicology Research, said the brains of black patients studied had significantly higher levels of IL-1beta, TNF-related apoptosis-inducing ligand (TRAIL), and monokine induced by gamma interferon (MIG).
Berman, "y interferon is the lymphokine and [beta] interferon the monokine responsible for inhibition of fibroblast collagen production and late but not early fibroblast proliferation," The Journal of Experimental Medicine, vol.
Essential oil of cinnamon bark (CBEO) from the species Cinnamomum zeylanicum depleted expressions of certain inflammatory cytokines, namely, interferon gamma-induced protein 10, interferon-inducible T cell alpha chemoattractant, monocyte chemoattractantprotein-1, and monokine induced by gamma interferon (MIG) in human dermal fibroblast system.
Masala et al., "Kidney posttransplant monitoring of urinary glycosaminoglycans/proteoglycans and monokine induced by IFN-[gamma] (MIG)," Clinical and Experimental Medicine, vol.
IL-6, IL-8 (CXCL8), IL-17, monokine induced by gamma interferon (MIG, CXCL9), IFN-[gamma], monocyte chemoattractant protein-1 (MCP-1, CCL2), interferon gamma-induced protein-10 (IP-10, CXCL10), TNF-[alpha], and regulated on activation, normal T cell expressed and secreted (RANTES) were quantified using the Bio-Plex suspension array platform together with Bio-Plex ProTM assay kits (Bio-Rad Laboratories Inc., Hercules, CA, USA) according to the manufacturer's instructions.
Feustel et al., "Mycophenolate mofetil-based immunosuppression and cytokine genotypes: effects on monokine secretion and antigen presentation in long-term renal transplant recipients," Transplantation, vol.
Chemokines whose concentrations were measured in the present study included CXCL8 (IL-8), CXCL9 (monokine induced by gamma interferon), CXCL10 (interferon-gamma-induced protein 10 [IP-10]), CXCL11 (interferon-inducible T-cell alpha chemoattractant), CCL4 (macrophage inflammatory protein 1[sz] [MIP-1[sz]]), CCL11 (eotaxin-1), CCL26 (eotaxin-3), CCL17 (thymus and activation-regulated chemokine [TARC]), CCL22 (macrophage-derived chemokine [MDC]), CCL2 (monocyte chemoattractant protein 1 [MCP-1]), and CCL13 (MCP-4).
Interferon-[alpha], interferon-inducible protein 10, monokine induced by interferon-[gamma], IL-6, monocyte chemoattractant protein-1, and IL-8 were detected on day 11 of illness but levels decreased as the patient clinically improved (online Technical Appendix Figure 3, panel B).
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.