Montelukast (10 mg/kg) treatment showed significant (p < 0.05) decrease in peribronchial and perivascular inflammatory infiltration as compared to AR control mice (Fig.
It was reported that rotenone--used in generating animal models of Parkinson's disease (PD)--increased CysLTR-1 expression in mouse microglial BV2 cell line [47,48] and that treatment with the CysLTR-1 antagonist montelukast prevented phagocytosis and cytokine release [48].
Objective: To evaluate and compare the protective effects of salbutamol and montelukast in amelioration of insulin induced airway hyper-reactivity on isolated tracheal smooth muscle of guinea pig in vitro.
His previous medications oral cetirizine 10 mg/day in morning and hydroxyzine 25 mg/day in evening along with montelukast sodium 10 mg/day along with xylometazoline nasal drops were continued.
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