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my·e·lo·fi·bro·sis

(mī′ə-lō-fī-brō′sĭs)

Proliferation of fibroblastic cells in bone marrow, causing anemia and sometimes enlargement of the spleen and liver.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

myelofibrosis

(ˌmaɪələʊfaɪˈbrəʊsɪs)

(Pathology) a disorder which causes fibrosis of the bone marrow

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

my•e•lo•fi•bro•sis

(ˌmaɪ ə loʊ faɪˈbroʊ sɪs)
n.

the replacement of bone marrow by fibrous tissue, characteristic of leukemia and certain other diseases.

[1945–50]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

myelofibrosis - fibrosis of the bone marrow

fibrosis - development of excess fibrous connective tissue in an organ

Translations

my·e·lo·fi·bro·sis

n. mielofibrosis, fibrosis de la médula ósea.

English-Spanish Medical Dictionary © Farlex 2012

myelofibrosis

n mielofibrosis; primary — mielofibrosis primaria

Mentioned in

References in periodicals archive

(16.) Sole F, de Pablos JM, Woessner S, et al Coexistence of tetrasomy 8 and trisomy 8 in a case with myeloid metaplasia with myelofibrosis.

Polysomy 8 Syndrome: A Distinct Clinical Entity Comprising of Myelomonocytic/Monocytic Lineage Involvement in Acute Leukemia

The JAK2(V617F) tyrosine kinase mutation in myelofibrosis with myeloid metaplasia: lineage specificity and clinical correlates.

The Progress of Next Generation Sequencing in the Assessment of Myeloid Malignancies

Primary bone marrow fibrosis is observed in different clonal hematological disorders including chronic myeloproliferative diseases (CMPDs) like chronic myeloid leukemia, polycythemia vera, essential thrombocythemia, myelofibrosis and myeloid metaplasia, acute leukemias, especially in AML-M7, and in myelodysplastic syndromes (MDS) [1].

Hyperfibrotic myelodysplastic syndrome: a report of three cases from north India/Hiperfibrotik miyelodisplastik sendrom: Kuzey Hindistan'dan uc olgu sunumu

Immune disorders in agnogenic myeloid metaplasia: relations to myelofibrosis.

Primary autoimmune myelofibrosis: a report of three cases and review of the literature/ Primer otoimmun miyelofibrozis-uc olgunun sunumu ve literaturun gozden gecirilmesi

Cytogenetic findings and their clinical relevance in myelofibrosis with myeloid metaplasia. Br J Haematol 2001;113:763-71.

Complex cytogenetic findings in the bone marrow of a chronic idiopathic myelofibrosis patient / Kronik idiopatik myelofibrozis olgusunun kemik iliginde kompleks sitogenetik bulgular

A phase 2 trial of combination low dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia. Blood 2003; 101:2534-41.

Mega-dose methylprednisolone (MDMP) for chronic idiopathic myelofibrosis / Kronik idiopatik miyelofibrosis icin yuksek doz metilprednizolon (YDMP)

The JAK2V617F tyrosine kinase mutation in myelofibrosis with myeloid metaplasia: Lineage specificity and clinical correlates.

The association between JAK2V617F mutation and bone marrow fibrosis at diagnosis in patients with philadelphia-negative chronic myeloproliferative neoplasms / Philadelphia Negatif kronik Miyeloproliferatif Neoplazili Hastalarin Tanisinda JAK2V617F mutasyonu ile Kemik Iligindeki Fibrozun Iliskisi

Perirenal extramedullary hematopoiesis in agnogenic myeloid metaplasia: MR imaging findings.

Radiological case of the month: Kichun Jason Lee, MD and William D. Boswell, MD

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