Abnormal ocular alignment frequently results from damage to the intranuclear portion of the gaze system, including: cranial nerves (CN) III (oculomotor), IV (trochlear), and VI (abducens), or the myoneural junction or extraocular muscles they innervate.
Tetanospasmin then enters the nervous system peripherally at the myoneural junction and is transported centripetally into neurons of the central nervous system (CNS).
(20) Initial bradycardia, bradypnea, and recumbency were likely related to effects of envenomation on vascular endothelium, peripheral nerve endings, and myoneural junctions, (21) as opposed to an allergic or anaphylactic reactions, which generally demonstrate tachycardia.
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