Prostigmin

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(redirected from neostigmine bromide)
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Noun1.Prostigmin - a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravis
anticholinesterase - a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect
brand, brand name, marque, trade name - a name given to a product or service
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In clinical practice, the dosage of neostigmine for the reversal of residual neuromuscular block is 20–70 [micro]g/kg.[sup][2],[16] Neostigmine has a ceiling effect, and the use of doses higher than 70 [micro]g/kg not only could not strengthen the reversal effects but also would increase the incidence of side effects.[sup][2],[16] As the molecular weight of neostigmine bromide is 303 g/mol and the steady-state volume of distribution is approximately 0.5 L/kg,[sup][17] its plasma concentration was calculated to be 0.13–0.46 [micro]mol/L.
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