After sciatic nerve damage, local Schwann cells can shed off the myelin sheaths and transform to a neuroblast status, where their proliferation and migration capacities can help to sweep away myelin remnants and generate a conduit for the axonal pathfinding, and consequently form the beneficial conditions for neurite outgrowth (1-3).
Effects of curcumin (Curcuma longa) on learning and spatial memory as well as cell proliferation and neuroblast differentiation in adult and aged mice by upregulating brain-derived neurotrophic factor and CREB signaling.
Interestingly, previous studies demonstrated that miR-183 and miR-200 gene families regulate cell proliferation in human glioblastoma cells [70, 71] and are involved in the equipoise between neuroepithelial proliferation and neuroblast emergence in the optic lobe of flies [72].
During embryogenesis the neuroectoderm divides to give rise to neuroepithelium which further divides into neuroblast, the spongioblast and the primitive ependymocytes.
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.