Phenotypic nonspecificity is observed for HD containing TFs in the induction of wingless, eyeless, arista to tarsus transformations, ectopic thoracic beards, Hox-mediated control of autophagy, suppression of spalt expression phenotypes following ectopic expression and the rescue of
neuromere development and mesoderm formation.
The boundaries of the metamere do not coincide with the boundaries of the segmental
neuromere and epidermis [17, 18], but they coincide with the parasegmental boundaries.
The rostral region of vertebrate neural tubes develops into three morphologically distinct swellings or the primary brain vesicles by differential proliferation of neuroepithelial territories: the forebrain, midbrain, and hind brain (Ishikawa et al., 2012), each of brain vesicles may be composed of several smaller repetitive units known as
neuromeres (Nieuwenhuys, 1998).