ni·fed·i·pine

(nī-fĕd′ə-pēn′)

A calcium channel blocker drug, C₁₇H₁₈N₂O₆, that acts as a coronary vasodilator and is used primarily to treat hypertension and angina pectoris.

[ni(tro)- + alteration of phe(nyl) + di(hydro)p(yr)idine, class of drugs to which it belongs.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

nifedipine

(naɪˈfɛdɪpiːn)

(Pharmacology) med a calcium-channel blocker used in the treatment of hypertension, angina pectoris, and heart failure

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

nifedipine - calcium blocker (trade name Procardia); appears to increase the risk of recurrent heart attacks

Procardia

calcium blocker, calcium-channel blocker - any of a class of drugs that block the flow of the electrolyte calcium (either in nerve cell conduction or smooth muscle contraction of the heart); has been used in the treatment of angina or arrhythmia or hypertension or migraine

Translations

nifedipine

n nifedipino, nifedipina

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References in periodicals archive

Experts' evaluation of the quality of antihypertensive drugs in Lagos State indicates that the prevalence of falsely labelled and substandard nifedipine tablets, the most commonly used drug to treat hypertension is high.

76.5% Of Hypertension Drugs On Sale In Lagos Are Bad -Study

The study examined if nifedipine and amlodipine, dihydropyridines widely used for high blood pressure and angina, are linked with out-of-hospital cardiac arrest.

Drug prescribed to BP patients can increase risk of sudden cardiac arrest, claims study

I also address the management of preeclampsia with severe features, and I share an algorithm that I have developed and fine-tuned over the years to control acute severe hypertension with the use of intravenous labetalol, intravenous hydralazine, or oral nifedipine.

Management of hypertensive disorders in pregnancy

Objective: To compare the outcome of oral Nifedipine and intravenous Labetalol in severe pregnancy induced hypertension in terms of time taken to achieve the target blood pressure.

ACUTE MANAGEMENT OF HYPERTENSIVE EMERGENCIES IN PREGNANCY: ORAL NIFEDIPINE VERSUS INTRAVENOUS LABETALOL

Drugs used for tocolysis include nifedipine, isoxsuprine, MgSo4, ritodrine, terbutaline and indomethacin.

A NON-RANDOMISED CONTROLLED TRIAL STUDY BETWEEN NIFEDIPINE AND ISOXSUPRINE AS TOCOLYTICS FOR PRE-TERM LABOUR

Thus the present study was undertaken to evaluate the anticonvulsant activity of nifedipine, which is a dihydropyridine calcium channel blocker (CCB), and of flunarizine, which is a difluorinated piperazine derivative, and act as selective calcium entry blocker, on maximal electroshock seizures (MES) induced seizures.

Anticonvulsive effects of nifedipine and flunarizine on maximal electroshock seizures induced seizures

We present a case report of a patient without any structural cardiac defects who developed atrial fibrillation following the administration of nifedipine as a tocolytic agent.

Atrial Fibrillation as a Rare Complication of the Use of Nifedipine as a Tocolytic Agent: A Case Report and Review of the Literature

Objective: To find out the effectiveness of oral nifedipine as a tocolytic agent in external cephalic version.

EFFECTIVENESS OF NIFEDIPINE IN EXTERNAL CEPHALIC VERSION

The pharmacist noted that the "pearly oval structures" were his nifedipine extended release pills (Figure 2) that were passing undigested through his alimentary tract.

Undigested Pills in Stool Mimicking Parasitic Infection

They also observed that the patients taking diltiazem generally had more petechiae than those taking nifedipine. They even suggested that purpura, either spontaneous or provoked is a pharmacological class effect rather than idiosyncratic and this may be a clue to diagnosis of internal or postsurgical bleeding.

Purpura and bleeding due to calcium channel blockers: A preliminary study