oxaprozin

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ox·a·pro·zin

 (ŏk′sə-prō′zĭn)
n.
An anti-inflammatory and analgesic drug of the NSAID class, C18H15NO3, used primarily to treat osteoarthritis and rheumatoid arthritis.

[oxaproz- (blend of oxazole, one of its constituents propionic acid) + -in.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.oxaprozin - a nonsteroidal anti-inflammatory drug (trade name Daypro)
nonsteroidal anti-inflammatory, nonsteroidal anti-inflammatory drug, NSAID - an anti-inflammatory drug that does not contain steroids; "NSAIDs inhibit the activity of both Cox-1 and Cox-2 enzymes"
propanoic acid, propionic acid - a liquid fatty acid found in milk and sweat and in fuel distillates
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive
nabumetone, naproxen, oxaprozin, piroxicam, salsalate, sulindac,
Oxazolone and its derivatives make a prominent structure of number of well established marketed drugs such as rilmenidine, furazolidone, nifurantoin, oxaprozin, and especially linezolid, which is an active against methicillin-resistant Staphylococcus aureus.
Ni(II) complex with oxaprozin, a hydrophobic antiproliferative agent, was synthesized and loaded into the P(HPA/IA) hydrogels.
Uscumlic, "Synthesis, characterization and antiproliferative activity of transition metal complexes with 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid (oxaprozin)," Chemical and Pharmaceutical Bulletin, vol.
NSAID classification Non-selective inhibition Acetic acid Proprionic acid Fenamate derivatives derivatives derivatives * Diclofenac * Fenoprofen * Meclofenamate * Etodolac * Flurbiprofen * Mefenamic acid * Indomethacin * Ibuprofen * Sulindac * Ketoprofen * Tolmetin * Naproxen * Oxaprozin Naphthyl alkanone Salicylates * Nabumetone * Aspirin * Diflunisal * Choline magnesium trisalicylate * Salicylate Enolic acid derivatives * Piroxicam * Meloxicam Selective COX-2 inhibition * Celecoxib * Rofecoxib Table 9.
Classic antidepressants reboxetine, amitriptyline and rice oxaprozin all played antidepressant role through regulating MAPK/ERK signaling pathway (Di Benedetto et al.
Greenstone LLC has launched oxaprozin caplets, an authorized generic of Pfizer Inc.'s Daypro.
All patients used NSAIDs: nonselective were used by 7 patients (19%; ibuprofen, diclofenac, ketoprofen, tiaprofenic acid, and oxaprozin), COX-2 preferential NSAIDs by 12 patients (32%; nimesulide and meloxicam), and COX-2 selective NSAIDs by 4 patients (11%; celecoxib).
False-positive results might arise if a patient is taking sympathomimetics such as Vicks nasal inhaler, tricyclic antidepressants, bupropion, selegiline, ranitidine (false-positive amphetamine results); sertraline or oxaprozin (false-positive benzodiazepine results); efavirenz or hemp-containing foods (cannabis); or poppy seeds, dextromethorphan, rifampin, or quinolones (false-positive opioid results).
Nine traditional NSAIDs (aspirin, etodolac, ibuprofen, indomethacin, ketorolac, meloxicam, naproxen, oxaprozin, and tolmetin) and one selective COX-2 NSAID (celecoxib) currently have Food and Drug Administration--approved pediatric indications.
* NSAIDs, long half-life, non-COX-selective, longterm use (naproxen, oxaprozin, piroxicam)
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