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Noun

pancreatic fibrosis - the most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known

cystic fibrosis, fibrocystic disease of the pancreas, mucoviscidosis, CF

monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes

fibrosis - development of excess fibrous connective tissue in an organ

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References in periodicals archive

These findings suggested the goose experienced zinc toxicosis with resultant pancreatic fibrosis and insufficiency resulting in diabetes mellitus, with cerebellar degeneration and necrosis attributed to persistent hyperglycemia.

Diabetes Mellitus With Concurrent Cerebellar Degeneration and Necrosis in a Domestic Goose (Anser anser domesticus)

The second is the oxidative pathway, which activates the stellate cells, leading to pancreatic fibrosis. It has demonstrated that both human and rat stellate cells are activated directly by ethanol in clinically relevant concentrations that go from 10 mM (social consumption) to 50 mM (intense ethanol consumption) (Apte et al., 2000; Masamune et al., 2010).

Ethanol Intake and Toxicity: In Search of New Treatments/Ingesta de Etanol y Toxicidad: En Busqueda de Nuevos Tratamientos

One patient had pseudopancreatic cyst by ultrasound abdomen and one patient had pancreatic fibrosis. Pleural fluid was exudates in all the patients by Light's criteria.

Study of Pleural effusions of pancreatic aetiology in a tertiary care centre

Recent studies have reported that TGF-[beta] has a predominant role in the accumulation of pathological extracellular matrix in pancreatic fibrosis and chronic pancreatitis (7).

Galunisertib (LY2157299), a transforming growth factor-p receptor I kinase inhibitor, attenuates acute pancreatitis in rats

Hepatic and pancreatic stellate cells (HSCs and PSCs) have been considered to be closely associated with the pathogenesis of fibrosis, offering a hopeful therapeutic target for treating hepatic and pancreatic fibrosis. Recently, we have generated transgenic mini-pigs carrying astrocyte-specific expression of DsRed regulated by the 2.2-kb human glial fibrillary acidic protein (hGFAP) gene promoter.

Human Glial Fibrillary Acidic Protein Gene Promoter Targets Hepatic and Pancreatic Stellate Cells in Transgenic Bama Mini-Pigs