par·a·log

or par·a·logue (păr′ə-lôg′, -lŏg′)

A gene that is related to another gene in the same organism by descent from a single ancestral gene that was duplicated and that may have a different DNA sequence and biological function.

[Back-formation from paralogous : para- (in reference to the parallel descent of the two genes from a single ancestral gene) + (homo)logous.]

pa·ral′o·gous (pə-răl′ə-gəs) adj.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

paralogue

(ˈpærəˌlɒɡ)

either of a pair of genes derived from the same ancestral gene

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

References in periodicals archive

GH-1 along with other members of the paralogue is a set of highly polymorphic genes (Chen et al., 1989).

Polymorphism and Allele Frequency Variation in Proximal End of Promoter and Exon 1 of Human Growth Hormone Gene in Pakistan - A Pilot Study

Since the observed phenotype of the transgenic lines and the gene expression data suggest regulation of the AtSPL paralogue genes in tobacco by Cg1, we searched for the Cg1-binding sites in the putative SPL sequences using the targetfinder.pl software [41].

The Maize Corngrassl miRNA-Regulated Developmental Alterations Are Restored by a Bacterial ADP-Glucose Pyrophosphorylase in Transgenic Tobacco

Additionally, RNA-binding motif protein 15 (RMB15) and its paralogue RMB15B recruits the METTL3-WTAP complex to m6A consensus sites for methylation [63].

N6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell Fate

Paralogue annotation method [17] was used to further assess pathogenic effect of variants.

Multifactorial Origin of Exertional Rhabdomyolysis, Recurrent Hematuria, and Episodic Pain in a Service Member with Sickle Cell Trait

C1q/TNF-[alpha]-related protein isoform 5 (CTRP5) has been identified as an adiponectin paralogue and is mainly expressed in adipose tissue, which shares functional and structural similarities to adiponectin [13-19].

IFI16 is in the same paralogue with pyrin and is an HIN domain family member 1 (PYHIN1 or IFIX), myeloid cell nuclear differentiation antigen (MNDA), and absent in melanoma 2 (AIM2) on human chromosome 1 as a human HIN-200 gene cluster.

Sex Differences in Correlation with Gene Expression Levels between Ifi200 Family Genes and Four Sets of Immune Disease-Relevant Genes

Being a huge fun of paralogue theatre, I loved the fact that love, dying romance per se, was presented as a corpse with geometrical progress growing inside the house.

A minute with Maria Papacosta Actress

Increased levels of 17-OHP, androstenedione, and testosterone are thought to occur due to preserved activity of 3[beta]-HSD1 encoded by a paralogue gene HSD3B1 expressed postnatally in skin and placenta (13).

Uniparental Isodisomy of Chromosome 1 Unmasking an Autosomal Recessive 3-Beta Hydroxysteroid Dehydrogenase Type II-Related Congenital Adrenal Hyperplasia

Interestingly, the depletion of the paralogue ilv3B resulted in fungal avirulence in any infection model [61].

Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi

Stanier et al., "Analysis of the planar cell polarity gene Vangl2 and its co-expressed paralogue Vangl1 in neural tube defect patients," American Journal of Medical Genetics, vol.

Spina Bifida: Pathogenesis, Mechanisms, and Genes in Mice and Humans