pen·tox·if·yl·line

(pĕn′tŏk-sĭf′ə-lēn′, -lĭn, pĕn-tŏk′sə-fĭl′ēn′, -ĭn)

A drug, C₁₃H₁₈N₄O₃, that decreases blood viscosity and improves blood flow, used to treat intermittent claudication.

[pent(yl) + oxy- + alteration of (theo)phylline.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

pentoxifylline - a drug (trade name Trental) used to treat claudication; believed to increase the flexibility of red blood cells so they can flow through the blood vessels to the legs and feet

Trental

drug - a substance that is used as a medicine or narcotic

Translations

pentoxifylline

n pentoxifilina

Mentioned in

References in periodicals archive

Dapsone, colchicine, pentoxifylline, and thalidomide can be effective for episodic treatment and prophylaxis, he said, warning against the use of thalidomide and other tumor necrosis factors in women who are of childbearing age.

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Of the two FDA-approved pharmacologic agents for treating claudication, data suggest that cilostazol is superior to pentoxifylline. But cilostazol is contraindicated in patients with any degree of heart failure, due to concerns about arrhythmia.

Test diabetic patients over age 50 for PAD: study suggests about 20% of patients with peripheral arterial disease are also diabetic

ExonHit Therapeutics, Paris, France, the alternative splicing- based drug discovery company, has initiated its first clinical trial evaluating EHT 0201 (pentoxifylline) in patients suffering from Amyotrophic Lateral Sclerosis (ALS).

EXONHIT INITIATES PHASE II CLINICAL TRIAL FOR EHT 0201

Half the animals were then given the cancer drug Pentoxifylline to test its effectiveness at fighting the infection and improving blood supply.

Pets and their People: BLOODY OUTRAGE; Storm as pigs are tortured by MoD scientists in worst test so far

Exemplary compositions in this class include: pentoxifylline; isobutylmethyl xanthine; ciprofloxacin; rolipram; terferol; and the quinolones generally.

University of Rochester obtains United States patent

Oral pentoxifylline (Trental [R]) has improved the outcome of some patients with sickle cell leg ulcers.

Sickle cell leg ulcers

Finally they settled on "Pentoxifylline" which is pleasant sounding and somewhat familiar.

Coffee and cold feet

Some of the medicines, such as aspirin, lithium, ACE inhibitors, ciclosporin, pentoxifylline, warfarin and methotrexate, interact with ketoprofen leading to various complications.

Expansion of Ketoprofen Market by 2020 to Gain Robust Traction

Some studies show possible benefits of pentoxifylline, vitamin E combination (7).

Radiation Fibrosis Syndrome Imitating Breast Cancer Recurrence; A Case Report

Pentoxifylline and acetylsalicylic acid treatment were administered.

Bilateral optic neuropathy, acral gangrene and visceral ischaemia as a rare presentation of calciphylaxis: A case report

However, hydroxychloroquine works well for skin disease, chloroquine helps combat hypercalcemia, and pentoxifylline and thalidomide can be helpful in cases of treatment-resistant lupus pernio.

Small fiber neuropathy common, vexing in sarcoidosis