pep·sin

also pep·sine (pĕp′sĭn)

1. A digestive enzyme found in gastric juice that catalyzes the breakdown of protein to peptides.

2. A substance containing pepsin, obtained from the stomachs of hogs and calves and used as a digestive aid.

[Greek pepsis, digestion (from peptein, to digest; see pek^w- in Indo-European roots) + -in.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

pepsin

(ˈpɛpsɪn) or

pepsine

(Biochemistry) a proteolytic enzyme produced in the stomach in the inactive form pepsinogen, which, when activated by acid, splits proteins into peptones

[C19: via German from Greek pepsis, from peptein to digest]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

pep•sin

(ˈpɛp sɪn)

n.

1. an enzyme, produced in the stomach, that in the presence of hydrochloric acid splits proteins into proteoses and peptones.

2. a commercial preparation containing pepsin, obtained from hog stomachs, used chiefly as a digestive and as a ferment in making cheese.

[1835–45; < Greek péps(is) digestion (pep-, base of péptein to digest + -sis -sis) + -in¹]

pep·sin

(pĕp′sĭn)

A powerful enzyme that breaks down proteins in the stomach of vertebrate animals.

The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

pepsin

A protein-digesting enzyme in the stomach.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

pepsin - an enzyme produced in the stomach that splits proteins into peptones

gastric acid, gastric juice - digestive secretions of the stomach glands consisting chiefly of hydrochloric acid and mucin and the enzymes pepsin and rennin and lipase

enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions

Translations

pepsina

pepsin

[ˈpepsɪn] N → pepsina f

Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

pepsin

n → Pepsin nt

Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

pepsin

[ˈpɛpsɪn] n → pepsina

Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

pep·sin

n. pepsina, enzima principal del jugo gástrico.

English-Spanish Medical Dictionary © Farlex 2012

pepsin

n pepsina

Mentioned in

References in classic literature

Between blasts she resorted to Epictetian philosophy in the form of pepsin chewing gum.

View in context

They had curled-hair works for the cattle tails, and a "wool pullery" for the sheepskins; they made pepsin from the stomachs of the pigs, and albumen from the blood, and violin strings from the ill-smelling entrails.

View in context

He suffered from dyspepsia, and he might often be seen sucking a tablet of pepsin; in the morning his appetite was poor; but this affliction alone would hardly have impaired his spirits.

View in context

In 91% (out of 65) samples from children undergoing myringotomy for OME, pepsin/pepsinogen levels in the middle ear effusion samples were up to 1000 times higher than serum levels, indicating that pepsin in the middle ear was almost certainly due to reflux of gastric contents.

Helicobacter pylori in Otorhinolaryngology: Cause or Bystander

Throughout the culture, larvae samples were homogenized in 200 mg [mL.sup.-1] of the mix of 100 mmol [L.sup.-1] of glycine-HCl buffer pH 2 for acid activity (pepsin) and with Tris-HCl 30 mmol [L.sup.-1] buffer + CaCh 12.5 mM pH 7.5 for alkaline enzyme activity.

Changes of digestive enzymes in totoaba (Totoaba macdonaldi Gilbert, 1890) during early ontogeny

Pepsin hydrolysis: Casein ([alpha]-S1) (10 mg) was solubilized in 1mL 0.1M HCl.

STUDY OF THERMAL AND HYDROLYTIC DENATURATION OF CASEIN ([alpha]S1) USING DIFFERENTIAL SCANNING CALORIMETRY (DSC)

In 2012, a study by Koufman and Johnston found that the addition of alkaline drinking water (pH 8.8) instantly denatured pepsin, in addition to acting as an acid buffer.

Unforeseen consequence of alkaline water therapy for laryngopharyngeal reflux

Refluxate may contain pepsin and bile contents that have also been implicated in tissue injury in the laryngopharynx (20,21).

Benchmarking of a Simple Scintigraphic Test for Gastro-oesophageal Reflux Disease That Assesses Oesophageal Disease and Its Pulmonary Complications/Basit Bir Yontem Olan Gastro-ozefageal Reflu Sintigrafisi ile Ozefagus Hastaligi ve Pulmoner Komplikasyonlarin Degerlendirilmesi

The pathophysiology of LPR differs somewhat from that of GERD, in that injury to laryngeal tissue appears to be due primarily to pepsin, rather than to acid.

Laryngopharyngeal Reflux: A Common Condition Treatable by Diet

Pepsin was noted to be active in 14.4% of 152 subjects who underwent tympanostomy tube placement [6].

A Clinical Trial of Proton Pump Inhibitors to Treat Children with Chronic Otitis Media with Effusion

Proteins in cheese are thought to be easily hydrolyzed in a gastric environment because of the presence of hydrochloric acid and pepsin. However, recent findings have shown that this environment may impede the digestion of cheese.

Examine impact of gastric environment on cheese digestion