In the peritoneal fluid, DBP gets converted to MAF (formation involves the cleavage of galactose and sialic acid residues by 3-galactosidase and a sialidase enzyme secreted by B and T lymphocytes).2 Due to increased conversion to MAF in the peritoneal fluid, the levels of DBP are, therefore, found to be lower in females with endometriosis.
Records for patients diagnosed with positive peritoneal fluid or pleural fluid of gynecologic/peritoneal origin (n = 113) and treated at the Cooper University Hospital (Camden, New Jersey) were retrospectively obtained for the years 2011 to 2015.
Chest and abdominal cavity puncture were performed and the result confirmed chylothorax and chyloperitoneum, and the amount of pleural and peritoneal fluid was gradually reduced.
Given the increase in peritoneal fluid in the presence of mild endometriosis and the presence of higher levels of CA 125 in peritoneal fluid compared to corresponding serum levels [34], this could also contribute to elevated serum CA 125 measurements.
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