The Company's immuno-regulatory product candidates include ProTmune, a
pharmacologically modulated, donor cell graft that is currently being evaluated in a Phase 2 clinical trial for the prevention of graft-versus-host disease, and a myeloid-derived suppressor cell immunotherapy for promoting immune tolerance in patients with immune disorders.
The compound was developed and
pharmacologically characterized by Aloke Dutta, Ph.D., professor of Pharmaceutical Sciences at Wayne State University, with funding from a National Institutes of Health grant, and the patents covering the compounds were licensed to TRImaran Pharma.
One of the clinical objectives of the study is to demonstrate that the product can be effectively used where the patient does not need to be either physically or
pharmacologically stressed for the study.
The neem tree has so many medicinal uses (it contains more than 100
pharmacologically active substances), in fact, that in India, it's been called 'the village pharmacy.' It's no surprise, then, that neem oil has been used for hundreds of years in traditional Indian medicine and ayurveda.
"Observing this, we asked ourselves if it was possible to
pharmacologically induce immune quiescence with medication that was better assured of reaching the point of infection," said Ho.
According to a notification, Ashharuz Zaman s/o Zafaruz Zaman got degree in the subject of Chemistry after approval of his thesis entitled 'Synthesis of Fused Quinolines as Potential
Pharmacologically Active Compounds'.
He lamented that Tobacco contains more than 4000 poisonous elements including
pharmacologically active mutagenic, cytotoxic and Carcinogenic causing different types of cancers in different organ of the body.
Applied to the lower eyelids once nightly, XAF5 penetrates the skin and acts
pharmacologically on fat cells to shrink undereye bags.
And we must always remember that simply because something may or may not be a cardiovascular risk factor, altering it
pharmacologically does not always mean that we will lower risk.
Moll explains that the methods researchers used to treat the mutp53 cancers are twofold: genetic ablation of the mutp53 gene and
pharmacologically attacking the molecular apparatus that is responsible for stabilization of mutp53.