plasma cell

Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, and lymph nodes. Also called plasmacyte.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

plas′ma cell`

an antibody-secreting cell, derived from B cells, that plays a major role in antibody-mediated immunity. Also called plas•ma•cyte (ˈplæz məˌsaɪt)

[1885–90]

plasma cell

A cell that produces antibodies as part of an immune response. B cells develop into plasma cells. See Note at antibody.

The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

plasma cell - a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood

plasmacyte

lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection

plasmablast - the precursor of a plasma cell

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References in periodicals archive

Multiple myeloma is cancer that begins in plasma cells (white blood cells that produce antibodies) and may also be referred to as plasma cell myeloma.

FDA approves Xpovio and dexamethasone for refractory multiple myeloma

Scattered lymphocytic and plasma cell infiltrates with abundant dense hyalinized collagenous stroma and focal small calcifications are seen.

Calcifying fibrous pseudotumour of maxilla: A rare entity mimicking malignancy: A case report

angular, contact, exfoliative, actinic, glandular, granulomatous, plasma cell cheilitis, simplex, etc.

DIFFERENTIAL DIAGNOSIS OF CHEILITIS - HOW TO CLASSIFY CHEILITIS?/DIFFERENCIJALNA DIJAGNOZA HEILITISA - KAKO KLASIFICIRATI HEILITIS?

Background and Objectives: Monoclonal gammopathy of undetermined significance (MGUS) is the most prevalent among the group of disorders called Plasma cell dyscrasias.

PREVALENCE OF MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE IN A TERTIARY CARE HOSPITAL OF LAHORE

The study was conducted using Plasma Cell Enrichment Technique, which is a more accurate mechanism for separating plasma cells from other cells during testing.

Study renders insights into genetic abnormalities leading to multiple myeloma

The diagnosis involves establishing high circulating levels of IgG4 > 135 mg/dL, increased serum IgG4 to IgG ratio of >8%, immunohistochemistry showing dense lymphoplasmacellular inflammatory infiltrate consisting of IgG4-positive plasma cells with storiform fibrosis and obliterative phlebitis, and increased IgG4 positive plasma cell > 10 cells per high-power field when at least three fields are evaluated and the IgG4/IgG ratio of RT is increased by varying degrees [7, 10].

Does the Intensity of IGG4 Immunostaining Have a Correlation with the Clinical Presentation of Riedel's Thyroiditis?

Solitary bone plasmacytoma (SBP) is a localized plasma cell tumor accounting for 2-5% of plasma cell malignancies.

C2 Solitary Bone Plasmacytoma Curettage and Vertebral Augmentation in an 83-Year-Old Female: Case Report and Review of Surgical Treatment Approaches in the Spine

As there was no evidence to suggest a lymphoma or a plasma cell neoplasm, a diagnosis of IgG-related disease was considered.

Immunoglobulin G4 Sclerosing Cholangitis: An Unusual Cause of Obstructive Jaundice--Case Report and Literature Review

Plasma cell myeloma (PCM) accounts for approximately 1.6% of all cancer cases and about 10% of all hematologic malignancies in the United States [1] and is characterized by the proliferation of malignant plasma cells and subsequent increase of a monoclonal paraprotein in serum.

Concurrent Polycythemia of Undetermined Etiology and Smouldering Plasma Cell Myeloma

Her medical history was significant for extranodal marginal zone lymphoma, plasma cell dyscrasia and amyloidosis diagnosed one year earlier following biopsy of a right cheek mass.

Breast amyloidosis detected with 3D mammography

Histopathological findings showed an elevated number of mature plasma cells with an IgG4+/IgG+ plasma cell ratio >50% and the presence of numerous IgG4-positive plasma cells in the germinal zone without pathological lymphoid population.

Study of systemic disease IgG4. Usefulness of 2-[18F]-fluoro-2-deoxy-D-glucose--positron emission tomography/computed tomography for staging, selection of biopsy site, evaluation of treatment response and follow-up