pro·pyl·thi·o·u·ra·cil

(prō′pəl-thī′ō-yo͝or′ə-sĭl′)

Abbr. PTU A drug, C₇H₁₀N₂OS, that inhibits the synthesis of thyroid hormones and is used to treat hyperthyroidism.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

propylthiouracil

(ˌprəʊpɪlˌθaɪəʊˈjʊərəsɪl)

(Pharmacology) a white crystalline water-insoluble substance with an intensely bitter taste, used in medicine to treat hyperthyroidism. Formula: C7H2N2OS

[from propyl + thio- + uracil (uro-¹ + ac(etic) + -il -ile)]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

propylthiouracil - a crystalline compound used as an antithyroid drug in the treatment of goiter

organic compound - any compound of carbon and another element or a radical

Translations

propylthiouracil

n propiltiouracilo

Mentioned in

References in periodicals archive

63 years and 715 days to the "boxed warning": unmasking of the propylthiouracil problem.

Management of Thyrotoxicosis in Children and Adolescents: A Turkish Multi-center Experience

However, they are seen in a proportion less than 50% in the DILE associated with minocycline, propylthiouracil, and statins (3,44,45).

Carbamazepine-induced systemic lupus erythematosus: A case-based review

Propylthiouracil (PTU)-induced agranulocytosis treated with recombinant human granulocyte colonystimulating factor (G-CSF).

Soft Tissue Infection After Antithyroid Drug-Associated Agranulocytosis/ Antitiroid Ilacla Iliskili Agranulositoz Sonrasi Gelisen Yumusak Doku Infeksiyonu

Toxicities associated with 1-month treatment with propylthiouracil (PTU) and methimazole (MMI) in male rats.

Hyperthyroidism induced reversible hepatotoxicity a case report and brief review

5*, 5 mgevery 2 days; PSL, prednisolone; MMI, methimazole; PTU, propylthiouracil; T3, triiodothyronine; T4, thyroxine.

A Case of Thyrotoxicosis due to Simultaneous Occurrence of Subacute Thyroiditis and Graves' Disease

DiBartolomeo, "Apparent vasculitis associated with propylthiouracil use," Arthritis & Rheumatism, vol.

Nasal Septal Perforation in Propylthiouracil-Induced Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

showed that once daily administration of MMI was as effective as thrice daily administration of propylthiouracil in improving thyroid indices and clinical markers with higher drug compliance (83.3% versus 53.3%) [15].

Efficacy of Once Daily versus Divided Daily Administration of Low Daily Dosage (15 mg/Day) of Methimazole in the Induction of Euthyroidism in Graves' Hyperthyroidism: A Randomized Controlled Study

A 32-year-old male patient who has been receiving propylthiouracil treatment for toxic multinodular goiter since 10 years was admitted to our hospital because of persisting complaints of restlessness, fatigue, tremor, and heat intolerance.

A rare case of non-surgical vocal cord paralysis: Vocal cord hematoma

* PTU (propylthiouracil) is the preferred drug till 16 weeks gestation

Management of thyroid disorders in pregnancy: Recommendations made simple

Among the hypothyroid patients, majority were given tranexamic acid and thyroxine, and among hyperthyroid patients majority were given propylthiouracil.

THE ROLE OF THYROID HORMONE STATUS IN ABNORMAL UTERINE BLEEDING

All patients were treated with propylthiouracil or methimazole by a dose titration regimen.

Mean platelet volume in Graves' disease: A sign of hypermetabolism rather than autoimmunity?

B., Interest Karamunting Potential (Melastoma malabathricum L.) on Leaf Total Cholesterol and Triglycerides in Rats Induced Hyperlipidemia Males Propylthiouracil. Achievement..

SOURSOP LEAVES FOR REDUCING BLOOD CHOLESTEROL LEVEL IN WHITE MALE RATS (RATTUS NOVERGICUS)