prostate-specific antigen

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pros·tate-spe·cif·ic antigen

(prŏs′tāt′spĭ-sĭf′ĭk)
n. Abbr. PSA
A protease secreted by the epithelial cells of the prostate gland. Levels of the protease in blood serum are usually elevated in people with prostate cancer and other conditions such as prostatitis and benign prostatic hyperplasia, and serum level is often used as a screening test for prostate cancer.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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References in periodicals archive
Prostate-specific antigen and prostate volume: a meta-analysis of prostate cancer screening criteria.
KEY WORDS: Free prostate-specific antigen; Prostate; carcinoma.
The digital rectal exam, prostate-specific antigen and transrectal echography in the diagnosis of prostatic cancer.
Structure, function, and regulation of the enzyme activity of prostate-specific antigen. World J Urol 1993; 11 (4): 188-191.
Associations of demographic and lifestyle characteristics with prostate-specific antigen (PSA) concentration and rate of PSA increase.
Prostate-Specific Antigen (PSA) is a blood marker that can enable very early detection of the most common cancer striking men, thereby enabling curative therapies to be employed before metastasis strikes.
The second Danish study, also led by Dr Orsted, looked at whether prostate-specific antigen levels could predict prostate cancer incidence and mortality in the general population.
Further, prostate-specific antigen density (PSAD), the ratio of the serum to the size of the prostate calculated as total serum PSA divided by prostate volume has also been correlated as an improvement to total PSA for the prostate can-cer.
Research released last week from the journal Cancer showed that for those with the lowest baseline levels of prostate-specific antigen, or PSA, 24,642 men would have to be screened and 724 cases of prostate cancer would have to be treated to prevent one death.
Results of a Swedish study suggest that screening with the prostate-specific antigen (PSA) blood test may help reduce deaths from prostate cancer almost by half over 14 years.
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