The method entails applying on the skin a therapeutically effective amount of a cosmetic or dermatological composition that has
retinaldehyde and glycylglycine oleamide and at least one cosmetically or dermatologically acceptable carrier.
A newborn lethal defect due to inactivation of
retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment.
She says: "Vitamin A helps repair sun damage and induces collagen production, so use some form of vitamin A derivative in the evening - a retinol or
retinaldehyde cream - as tolerated.
Isotretinoin,
retinaldehyde and tazarotene are less studied than tretinoin, however their results are also promising.
Other forms of retinoid include retinyl palmitate and
retinaldehyde, which can be found in skin care products.
Mutations in genes such as RP1L1 [8q23.1], RLBP1 (
retinaldehyde binding protein 1) [15q26.1], CRB1 (crumbs family member 1) [1q31.3], ABCA4 (ATP-binding cassette subfamily A member 4) [1p22.1], RPE65 (retinal pigment epithelium-specific protein 65kDa) [1p31.2], and CNGB1 (cyclic nucleotide gated channel beta 1) [16q21] also share 1%, 1%, 6.5%, 2%, and 4%, respectively, in autosomal recessive inheritance.
Moreover, ALDH1, the dominant form in the family of ALDH involved in the conversion of
retinaldehyde to retinoic acid, is a recognized marker [117].
Goverse et al., "Expression of
retinaldehyde dehydrogenase enzymes in mucosal dendritic cells and gut-draining lymph node stromal cells is controlled by dietary vitamin a," The Journal of Immunology, vol.
Retinal, also named
retinaldehyde, is a polyene chromophore and is the basis for animal vision allowing the conversion of light into metabolic energy.
* Proprietary and Patent Protected Ingredients (Client Exclusivity; ex: Stabilized
Retinaldehyde)
Ray, "Cutting edge: inhaled antigen upregulates
retinaldehyde dehydrogenase in lung [CD103.sup.+] but not plasmacytoid dendritic cells to induce Foxp3 de novo in [CD4.sup.+] T cells and promote airway tolerance," The Journal of Immunology, vol.