strep·to·ni·grin

(strĕp′tə-nī′grĭn)

A highly toxic antibiotic, C₂₅H₂₂N₄O₈, produced by an actinomycete (Streptomyces flocculus) and active against various types of tumors.

[strepto- + Latin niger, nigr-, black; see nek^w-t- in Indo-European roots + -in.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

References in periodicals archive

While antibiotics display an enormous diversity in chemical structures, quinone antibiotics such as Adriamycin, Mitomycin C, and Streptonigrin deserve special attention [7-10].

Design and synthesis of novel isoxazole tethered quinone-amino acid hybrids

Streptonigrin antibiotics, trypan blue (6) and theophylline (7) may also have teratogenic effects resulting in otocephaly.

Otocephaly--a case report

Dynemicin A and streptonigrin are naturally occurring members of the class of antitumors, antibiotics whose synthesis are based on the utilization of performed quinoline derivatives [5].

Synthesis, physicochemical and antimicrobial studies of first row transition metal complexes with quinoline derivatives nitroquinolino[3,2-b] [1,5]benzodiazepine and nitroquinolino[3,2-b] [1,5]benzoxazepine

It is because certain metal ions are required for the activity and proper functioning of polypeptide antibiotics, such as bleomycin, streptonigrin, and bacitracin.

Production of Antimicrobial Metabolites by Bacillus subtilis Immobilized in Polyacrylamide Gel

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