sulfadiazine

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sul·fa·di·a·zine

 (sŭl′fə-dī′ə-zēn′)
n.
A sulfa drug, C10H10N4O2S, used in the treatment of toxoplasmosis and other infections.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

sulfadiazine

(ˌsʌlfəˈdaɪəˌziːn)
n
(Pharmacology) an important sulfa drug used chiefly in combination with an antibiotic. Formula: C10H10N4O2S
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sulfadiazine - a sulfa drug used in treating meningitis and pneumonia and other infections
sulfa, sulfa drug, sulfonamide, sulpha - antibacterial consisting of any of several synthetic organic compounds capable of inhibiting the growth of bacteria that require PABA
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Translations

sulfadiazine

n sulfadiazina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive
The bandage was changed every other day for 10 days with reapplication of the Vetericyn Plus as well as the addition of 1% silver sulfadiazine cream.
Current treatment guidelines for toxoplasmic encephalitis (TE) (1) recommend either pyrimethamine plus sulfadiazine or pyrimethamine plus clindamycin; trimethoprim/sulfamethoxazole is also known to have comparable potency (2).
Treatment recommendations for severe cases include discontinuing the responsible drug; using highly potent topical or intralesional corticosteroids for noneroded lesions; applying topical steroid with antibiotics, bacitracin, and silver sulfadiazine; wound dressings for eroded lesions; and systemic corticosteroids (18).
In these studies, Aloe vera was more effective than petroleum jelly gauze dressing, silver sulfadiazine 1% ointment, and framycetin cream.
Treatment with pyrimethamine, sulfadiazine and folic acid is used for patients who are immunocompromised and those immunocompetent patients with severe or persistent symptoms.4 Short course of corticosteroids can be used in toxoplasmosis encephalitis patients with significant cerebral edema and elevated intracranial pressure.
In addition, the researchers evaluated the dosimetric effect of topical agents by delivering 200 monitor units and measuring the dose at the surface and at a depth of 2 cm in a tissue-equivalent phantom with or without a petroleum-based ointment (Aquaphor, petrolatum 41 percent) and silver sulfadiazine cream, 1 percent.
The application of topical antibiotics like 1% silver sulfadiazine, sulfamylon, and 0.3% silver nitrate reduces contamination of the wound and allows partial thickness burns to heal.
([double dagger]) Anti-toxoplasma treatment with sulfadiazine (50 mg/kg BD), pyrimethamine (2 mg/kg/day for 2 days, then 1 mg/kg 3 times a week for the rest of the treatment period), and folinic acid (10 mg 3 times a week).
Antitoxoplasmosis agent Sulfadiazine, Antiviral agent's acyclovir, indinavir, and foscarnet used in the treatment of OIs caused by HIV, are all reported to cause intrarenal crystal deposition can cause AKI.
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