For example, the cancer drug
Taxol was first extracted from the bark and needles of the Pacific yew tree.
Two cycles neoadjuvant chemotherapy of
taxol and carboplatin (TC,
taxol 175 mg/m [sup]2, carboplatin area under the curve = 5, every 3 weeks) were added.
Taxol, an anti-cancer drug, is one of the most successful natural
Reportedly, there is currently no pharmaceutical
Taxol comparison to Paccal Vet in veterinary medicine.
"
Taxol, or chemotherapy drugs, are effective but toxic and hence we researched a way to deliver it using nano micilles (molecules suspended in liquid)," said the 47-year-old Egyptian researcher.
The micellar system has been used to send
taxol to intended spots for treating breast cancer in animal phases.
The chemotherapy drug paclitaxel (
Taxol) treats breast, lung, ovarian and other cancers.
Conclusion: Lower plants extracts were reported to exhibit better interactions with the
taxol and epothilone binding sites.
El
taxol se encontro por primera vez en extractos de la corteza de arboles de Taxus brevifolia y actualmente se extrae de otras especies de Taxus spp, lo que ha llevado a que los arboles se encuentren al borde de la extincion (Baebler et al., 2005).
For all in vitro experiments, the following TLR ligands and their combinations were used in the concentrations 0.01, 0.1, 1, and 10 [micro]M:
Taxol, R848 (Enzo Life Sciences, Lorrach, Germany), LPS (SigmaAldrich, Hamburg, Germany), and Poly I:C (InvivoGen, San Diego, CA, USA).
Marketed as Abraxane, nanoparticle albumin-bound (nab) paclitaxel was developed as an alternative to
Taxol, which delivers paclitaxel in a highly toxic cre-mophor solvent.