(a) PTT = activated partial thromboplastin time; INR = international normalized ratio; TT =
thrombin time. (a) Abnormal results.
Thrombin time is used to evaluate the conversion of fibrinogen to fibrin.
The maximum percentage reversal of the anticoagulant effect of dabigatran within 4 hours after the administration of idarucizumab was 100% [95% confidence interval (CI): 100-100] on the basis of the diluted
thrombin time or ecarin clotting time.
(i) A normal
thrombin time (TT) can effectively rule out presence of any significant serum level of dabigatran, though an elevated
thrombin time does correlate well with the serum dabigatran level.
The PT,
thrombin time, platelet count and function are normal.
This truncation was shown to 48,0 [+ or -] 1,1s to 24,0 [+ or -] 1,6s (P<0.001) and
thrombin time with a tendency to 9,3 [+ or -] 0,3s to 10,0 [+ or -] 1,6s up with increasing content free heparin.
Further, the patient was investigated for causes of spontaneous subdural hematoma including repeating his prothrombin time, activated partial
thrombin time, and DIC profile (
thrombin time: 10 sec; normal: 12-14 sec, fibrinogen level: 716 mg/dl; normal: 200-400 mg/dl, FDP--not detectable, Ivy's bleeding time: 4 min; normal: 2-7 min, clot solubility test: normal, D-dimer: 0.5 [micro]g/ml; normal: <0.5 [micro]g/ml).
The activated partial thromboplastin time (APTT) and the
thrombin time (TT) of the postoperative venous blood was 18.9 s and
This polymer had effect on the normal coagulation time by the activated partial thromboplastin time (APTT) and
thrombin time (TT) tests using human plasma, except for prothrombin time (TP) test.
Whole blood count, peripheral blood smear, blood group, ferritin, platelet function analyzer 100 (PFA-100), prothrombin time (PT), activated partial thromboplastin time (aPTT),
thrombin time (TT), fibrinogen, von Willebrand factor antigen (VWF:Ag), VWF ristocetin cofactor (VWF:RCo), factor VIII (F Viii), and platelet aggregation assays were performed.
(8) Other indicators for laboratory monitoring of DTI are Activated clotting time (ACT), Ecarin clotting time(ECT), Prothrombin -induced clotting time (PiCT),Diluted
thrombin time (Dtt).An increased focus has been placed on developing new laboratory tests suitable for the measurement of DTIs that are reproducible, accurate, and sensitive such as the ability to directly measure drug concentrations by mass spectrometry.