transforming gene

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Noun1.transforming gene - a gene that disposes normal cells to change into cancerous tumor cellstransforming gene - a gene that disposes normal cells to change into cancerous tumor cells
oncogene
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
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References in periodicals archive
Nash is also keeping his Buy rating on Bluebird Bio, saying he sees the company as "best positioned" in transforming gene therapy from a "scientific endeavor" to a "successful proposition."
Bluebird Bio price target lowered to $174 from $184 at SunTrust
Fulcrum Therapeutics is a biotechnology company developing new medicines to deliver a new future to patients and their families by transforming gene regulation in disease.
Fulcrum Therapeutics Appoints Biotech Executive Bryan Stuart as COO
Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.
Study of major genetic factors involved in pituitary tumorigenesis and their impact on clinical and biological characteristics of sporadic somatotropinomas and non-functioning pituitary adenomas
A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.
A Homozygous c.2536G>A Mutation in CRB1 Gene Manifesting Autosomal Recessive Retinitis Pigmentosa in a Large Consanguineous Kashmiri Family
(7) Many scientists might then have lost interest in GRPs owing to their lack of any association with malignancy, and moved onto the new field of "tyrosine phosphorylation" following the discovery in 1980 that the transforming gene product of Rous sarcoma virus phosphorylated tyrosine instead of serine or threonine.
The unfolded protein response: the dawn of a new field
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