Post.exposure rate of tuberculosis infection among health care workers measured with
tuberculin skin test conversion after unprotected exposure to patients with pulmonary tuberculosis: 6.year experience in an .talian teaching hospital.
Tuberculin skin test for the diagnosis of latent tuberculosis during renal replacement therapy in an endemic area: a single center study.
Comparison of inter-feron-gamma release assay versus
tuberculin skin test for tuberculosis screening in inflammatory bowel disease.
Alternatives to the
tuberculin skin test: interferon-[gamma] assays in the diagnosis of Mycobacterium tuberculosis infection.
Krueger et al., "Screening for latent tuberculosis infection: performance of
tuberculin skin test and interferon-gamma release assays under real-life conditions," Annals of the Rheumatic Diseases, vol.
Srivastava, "Steroids decrease prevalence of positive
tuberculin skin test in rheumatoid arthritis: implications on Anti-TNF therapies," Interdisciplinary Perspectives on Infectious Diseases, vol.
Distribution of respondents considering TST results in study (QFT positive) and control (QFT negative) groups TST test Study group Control group n % n % Negative reaction (no firm bump 29 19.33 146 97.33 (*) at the test site) Moderate positive reaction (firm bump 99 66.00 4 2.67 (*) of 5 mm (0.2 in.) in size) Strong positive 0 0 reaction 22 14.67 (firm bump of 10 mm (0.4 in.) in size) TST =
tuberculin skin test; QFT = QuantiFERON test; (*) statistically significant difference between control and study groups considering TST results Table 3.
In laboratory tests, widespread stromal infiltration was observed in the right lung and the left lung was normal on posterior-anterior chest X-ray; purified protein derivative (PPD)
tuberculin skin test resulted in a 15 mm induration (the patient had no TB vaccination scar); whole blood and biochemical values were normal; hepatitis serology was negative; HIV ELISA test was negative, serum angiotensin converting enzyme level was 73 U/L, serum calcium level was normal, Brucella agglutination test was negative, and syphilis serology was negative.
The two most effective screening tests,
tuberculin skin test and interferon-gamma release assays, demonstrated a sensitivity and specificity of 79% and 97%, and at least 80% and 95%, respectively.
The main method of testing in the US is a
tuberculin skin test, in which the animal receives an injection of tuberculin in the skin and is checked for a reaction 72 hours later.
The two most effective screening tests,
tuberculin skin test (TST) and interferon-gamma release assays (IGRA), demonstrated sensitivity and specificity of 79% and 97%, and at least 80% and 95%, respectively.
The
tuberculin skin test (PPD) can be a supportive diagnostic tool if positive, but anergy is seen more commonly among patients with disseminated TB (up to 68% of cases) than those with pulmonary or isolated extrapulmonary involvement.
tuberculin skin test - a skin test to determine past or present infection with the tuberculosis bacterium; based on hypersensitivity of the skin to tuberculin