ul·tra·cen·tri·fuge

(ŭl′trə-sĕn′trə-fyo͞oj′)

A high-velocity centrifuge used in the separation of colloidal or submicroscopic particles.

ul′tra·cen·trif′u·gal (-trĭf′yə-gəl, -trĭf′ə-gəl) adj.

ul′tra·cen·trif′u·gal·ly adv.

ul′tra·cen′tri·fu·ga′tion (-fyo͝o-gā′shən) n.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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Noun

ultracentrifugation - centrifugation at very high speeds

centrifugation - the process of separating substances of different densities by the use of a centrifuge

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References in periodicals archive

To improve exosome concentration and its quality, several technologies have been developed for exosome purification, among which ultracentrifugation and microfiltration, size exclusion chromatography(SEC), and immunoaffinity capture are favored.

New Progress Made in Exosome Research Services for Creative Biolabs

Until recently, the primary methods of assessing a patient's sdLDL-C levels were based on the laborious and time-consuming ultracentrifugation and electrophoresis methods.

Size matters: the true weight of risk in lipid profiling

In contrasts to above finding literature Kamezaki F et al have concluded that direct measuring LCLc methods over estimates, rather than underestimates LDLc results.20 Chotkowska et al have also highlighted mLDLc methods once compared with gold standard technique of ultracentrifugation to demonstrate a positive bias in comparison to Friedewald's equation.21 Taken together the contrasts in literature with regards to methodologies over and underestimating triglycerides, possible explanation could be: First of all, as the triglyceridemia affects LDLc measures in calculated methods which is evident by the use of different factors to manage VLDL in serum triglyceride calculation, so calculated methods are inherently biased to the presence of triglyceride adjustment.22,23

Friedewald's equation for calculating LDL-cholesterol: Is it the time to say "Goodbye" and adopt direct LDL cholesterol methods?

Based on the size and density of exosomes, we can collect exosomes by ultracentrifugation at 20,000 xg .

Urinary Extracellular Vesicle: A Potential Source of Early Diagnostic and Therapeutic Biomarker in Diabetic Kidney Disease

Lipoproteins are classified by ultracentrifugation into five major types, with increasing density and decreasing size: chylomicrons (CMs), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL).

Laboratory investigations in lipidology

We obtained a collection rate of over 99 percent, surpassing ultracentrifugation as well as other methods that are currently being used in the field."

Study finds nanowire device to detect cancer with a urine test

F4370), concentrated by ultracentrifugation and purified by sucrose gradient ultracentrifugation.

Determination of ferret enteric coronavirus genome in laboratory ferrets

To isolate the specific signal for chylomicrons from other contaminants that may cause false-positive identification of a chylous effusion, lipid analysis can be performed on fractions of the body fluid after ultracentrifugation that separates the more dense HDL/LDL fraction (the HL fraction, density > 1.006 g/L) from the less dense VLDL/chylomicron fraction (VL fraction, density <1.006 g/L) (7).

A Man with Recurrent Ascites after Laparoscopic Cholecystectomy

Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles