ve·rap·a·mil

(və-răp′ə-mĭl′)

A calcium channel blocker drug, C₂₇H₃₈N₂O₄, that acts as a coronary vasodilator and is used in its hydrochloride form to treat hypertension and certain cardiac arrhythmias.

[vera(tryl), one of its constituents (from New Latin Vērātrum, hellebore genus; see veratrine) + -pamil, vasodilating drug suffix (perhaps p(ropyl) + am(ino) + (nitr)il(e)).]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

verapamil

(vɪˈræpəˌmɪl)

(Pharmacology) med a calcium-channel blocker used in the treatment of angina pectoris, hypertension, and some types of irregular heart rhythm

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ve•ra•pam•il

(ˌvɪər əˈpæm əl, ˌvɛr-)

n.

a white, crystalline powder, C₂₇H₃₈N₂O₄, used as a calcium blocker in the treatment of angina and certain arrhythmias.

[1965–70]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

verapamil - a drug (trade names Calan and Isoptin) used as an oral or parenteral calcium blocker in cases of hypertension or congestive heart failure or angina or migraine

Calan, Isoptin

calcium blocker, calcium-channel blocker - any of a class of drugs that block the flow of the electrolyte calcium (either in nerve cell conduction or smooth muscle contraction of the heart); has been used in the treatment of angina or arrhythmia or hypertension or migraine

Translations

verapamil

n verapamilo, verapamil m

Mentioned in

References in periodicals archive

The COA said the BuCor received 99,300 Verapamil tablets for high blood pressure last year, but only 3,450 tablets were actually issued to inmate patients.

COA report: BuCor bought excess meds

Under the amended agreement, Recro Gainesville will continue to supply Teva with Verapamil SR capsules through 2024 and Teva will continue to be Recro Gainesville's exclusive U.S.

Recro, Teva Extend License And Supply Agreement

Under the terms of the amended agreement, Recro Gainesville will continue to supply Teva with Verapamil SR capsules through 2024 and Teva will continue to be Recro Gainesville's exclusive United States distributor of the product, for which Recro Gainesville is the new drug application holder.

Recro Pharma announces extension of supply agreement with CDMO division, Teva

All the anticonvulsants were stopped, and as flunarizine is not available in SA and topiramate could only be obtained through a patient-named motivation, it was decided to start him on verapamil in the interim.

Alternating hemiplegia of childhood: First South African case report and verapamil as a possible treatment option

Objective: To evaluate the efficacy of combined use of nitrate and calcium channel blocker (Verapamil) in prevention of radial artery spasm during coronary angiographies.

Efficacy of Nitrates and Calcium Channel Blocker in Prevention of Radial Artery Spasm during Coronary Angiographies

Mechanical stimulation has been shown to have a strong influence on chondrocyte biosynthetic activity.[2] Furthermore, multiple studies have suggested a regulatory role for intracellular Ca2+ in endochondral ossification, a process that includes chondrocyte proliferation, differentiation, and apoptosis.[3] Based on the above findings, we hypothesized that mechanical stress alone or in combination with the voltage-sensitive Ca2+ channel inhibitor verapamil would stimulate chondrocytes with respect to AGC biosynthesis.

Effect of Mechanical Stress in Combination with Verapamil on Levels of Aggrecan and ADAMTS-5 mRNAs and Proteins in Human Osteoarthritic Chondrocyte/Agarose Constructs

Vagal manoeuvres, beta-blockers, verapamil, and diltiazem are used to end acute episodes of PSVT and to reduce the frequency of chronic episodes.

The clinical picture was suggestive of a CH and the patient was medicated with verapamil 120 mg daily.

Cluster-Like Headache Secondary to Sphenoid Sinus Mucocele

In situ single pass intestinal perfusion was used to investigate the absorption sites of three constituents in the small intestine, as well as the influence of drug concentrations, concentrations of P-gp inhibitor verapamil hydrochloride, concentrations of MRP2 inhibitor probenecid, and concentrations of energy inhibitor 2,4-dinitrophenol, in order to discuss the absorption mechanism of the constituents and influent factors (5).

Absorption mechanism of three curcumin constituents through in situ intestinal perfusion method

It was learned that she had attempted suicide by verapamil overdose before the cardiac arrest.

A Report of Brugada Syndrome Presenting with Cardiac Arrest Triggered by Verapamil Intoxication