xeroderma pig·men·to·sum

(pĭg′mən-tō′səm)

A rare hereditary skin disorder caused by a defect in the enzymes that repair DNA damaged by ultraviolet light.

[New Latin xēroderma pigmentōsum : xēroderma, xeroderma + pigmentōsum, neuter of pigmentōsus, of pigment.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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Noun

xeroderma pigmentosum - a rare genetic condition characterized by an eruption of exposed skin occurring in childhood and photosensitivity with severe sunburn; inherited as a recessive autosomal trait in which DNA repair processes are defective so they are more likely to chromosome breaks and cancers when exposed to ultraviolet light

xeroderma, xerodermia - a mild form of ichthyosis characterized by abnormal dryness and roughness of the skin

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References in periodicals archive

While Charlie stands confused at the front door, a friend of Katie's explains that she has xeroderma pigmentosum.

'Midnight sun' and what it means to have XP

In a letter telling her about the award, Prime Minister Theresa May said: "By drawing on your own experiences as a family, you are providing vital support and guidance to patients and families living with xeroderma pigmentosum.

PM praises woman for awareness work about rare disease; Health: Aberdeen mum set charity up after son Eddison was diagnosed

Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy.

Cockayne Syndrome as a Rare Cause of Hemiplegia: Review of the Literature Accompanied by a Case Report/Nadir Bir Hemipleji Nedeni Olarak Cockayne Sendromu: Bir Olgu Sunumu Esliginde Literaturun Gozden Gecirilmesi

Xeroderma pigmentosum complementation group D polymorphism toward lung cancer susceptibility survival and response in patients treated with platinum chemotherapy.

Association of polymorphisms of xeroderma pigmentosum complementation group D gene with cervical cancer in Maharashtrian population: A case-control study

Keywords: Xeroderma Pigmentosum-Cockayne Syndrome complex (XP-CS), Xeroderma Pigmentosum (XP), Cockayne Syndrome (CS)

Xeroderma Pigmentosum - Cockayne Syndrome Complex (XP-CS) - Another case

Directed by Scott Speer, this English language remake of a 2006 Japanese film quickly distils the facts about a recessive condition called xeroderma pigmentosum (XP), which is triggered by exposure to sunlight.

ALSO SHOWING

In Midnight Sun , Thorne's character Katie Price is plagued by a rare genetic disease called xeroderma pigmentosum that causes extreme sensitivity to sunlight.

Patrick Schwarzenegger basks in 'Midnight Sun'

In addition to cumulative sun exposure, other risk factors for AK include fair skin, advanced age, exposure to carcinogens, prolonged immunosuppression, and genetic conditions affecting DNA repair mechanisms such as xeroderma pigmentosum [5].

A Rare Presentation of Actinic Keratosis Affecting the Tarsal Conjunctiva and Review of the Literature

In the differential diagnosis, Bazex-Dupre-Christol syndrome, Muir-Torre syndrome, Rombo syndrome, multiple papular trichoepitheliomata, and xeroderma pigmentosum should be considered.

Gorlin-Goltz syndrome

A study examining light sources in the environment of a child with xeroderma pigmentosum suggested that indoor lights emit unexpected amounts of UV light as measured by a spectral radiometer.

Why you should use sunscreens indoors

This outcome occurred, at least in part, because an enzyme that repairs UV-damaged skin - xeroderma pigmentosum group A (XPA) - shifted its daily cycle to be less active in the day.

Midnight snacker? Here's how you are risking your skin