zi·do·vu·dine

(zĭ-dō′vyo͞o-dēn′)

n. Abbr. ZDV

See AZT.

[Alteration and blend of azidothymidine and edoxudine, an antiviral drug having a similar structure (e(thyl) + d(e)ox(y)- + u(ri)dine), with -v- perhaps from antiviral.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

zidovudine

(zaɪˈdɒvjʊˌdiːn)

(Pharmacology) a drug that is used to treat AIDS. Also called: AZT

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

zi•do•vu•dine

(zaɪˈdoʊ vyuˌdin)

n.

the international generic term for azidothymidine. Compare AZT.

[1986; of undetermined orig.]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

zidovudine - an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow

AZT, Retrovir, ZDV

NRTI, nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs

Translations

zidovudine

n zidovudina

Mentioned in

References in periodicals archive

You tell me, if you were in their shoes, what would you do." The drugs, Nevirapine and Zidovudine, have been missing in a number of public health facilities across the country, causing concern among health workers that infected mothers will not be able to prevent their children from getting the virus.

69,000 newborns at risk due to ARVs shortage

Objective: To assess the incidence of zidovudine induced pigmentation among HIV-infected patients.

Zidovudine-induced pigmentation on skin, nail and oral cavity - a study on 119 patients

Ghana has since 2014 adopted this recommendation; however there is paucity of scientific data that reflects the safety and efficacy of the tenofovir-based therapy compared to zidovudine in the Ghanaian health system.

Tenofovir-Based Highly Active Antiretroviral Therapy Is Associated with Superior CD4 T Cells Repopulation Compared to Zidovudine-Based HAART in HIV 1 Infected Adults

(1,2) Various risk factors for HIV-related anaemia have been identified, including clinical AIDS, CD4+cell count <200cells/mm3, high plasma viral load, female sex, African American ethnicity, and Zidovudine use (3).

Clinical profile of anaemia among HIV infected patients and its correlation with CD4+ count

Pharmaceutical company Mylan (NasdaqGS:MYL) reported on Monday the market availability of its Lamivudine and Zidovudine Tablets USP, 150 mg/300 mg for the treatment of HIV-1 infection in combination with other antiretroviral (ARV) agents.

Mylan unveils generic Combivir in the US, strengthening its growing antiretroviral franchise in the nation

Zidovudine drug is known as the first anti-HIV drug in the world.

New Iran-Made Nanosensor Precisely Measures Level of Anti-HIV Drugs

Zidovudine (37-azido-3,-deoxythymidine; AZT) is a nucleoside reverse transcriptase inhibitor (NRTI) that inhibits the replication of the human immunodeficiency virus type 1 (HIV).

Pharmacokinetic and tissue distribution study of solid lipid nanoparticles of zidovudine in rats

They had been on zidovudine and lamivudine (brand names Retrovir and Epivir) for a median of roughly 5.5 years.

Antiretroviral switch linked to drop in BMD

When HIV is not diagnosed until women go into labor, their infants are usually treated soon after birth with the anti HIV drug zidovudine (ZDV), to prevent the infants from becoming infected with the virus.

New drug regimens cut HIV spread from mother to infant

All mothers and infants received perinatal prophylaxis with single-dose nevirapine and one week of zidovudine plus lamivudine.

Eliminating perinatal HIV infection with ARVs

In resource-limited settings, combination chemotherapy consisting of 2 nucleoside analogues (reverse transcriptase inhibitors) [either zidovudine (AZT) or stavudine (d4T) along with lamivudine (3TC)] and 1 non-nucleoside reverse transcriptase inhibitor (NNRTI) [either nevirapine (NVP) or efavirenz (EFV)] are frequently used.

Zidovudine-induced anaemia in HIV/AIDS