With many advanced types of cancer, certain tumor- associated antigens such as CEA (cancer embryonic antigen), PSA (prostate specific antigen) and MUC1 (cell surface associated mucin 1) are over-expressed (that is, produced in very large quantities) and aberrantly
expressed (produced in abnormal forms).
In this case, the heterophils were aberrantly
high, which resulted to monocytopenia or the lower count of monocytes.
We have been talking about low-value services, such as needless diagnostic scans, for decades, along with fraudulent billing, aberrantly
high prices and abnormally high administrative costs.
H3B-6527 has shown sustained tumor regressions in several preclinical models of HCC where FGF19-FGFR4 signaling is aberrantly
3) Synaptic dysfunction: p-tau is aberrantly
trafficked from axons to form aggregates in the somatodendritic compartment, thereby interfering with normal synaptic transmission.
For example, miR-30b regulates the normal and tumorigenic development of human neural tube cells whereas aberrantly
expressed miR-30b expression may result in schizophrenia (33).
However, it is common for acute leukemias to aberrantly
express protein markers more typically associated with other lineages, for example, expression of the myeloid markers CD13 and CD33 in B-ALL or T-ALL and expression of the T/NK-cell markers CD7 and CD56 in AML.
, Greinke agrees, asserting, "Ambiguity is fundamental to poetry, just as literal meaning is to prose.
Additionally, CagA presented on top of the TFSS pilus interacts with the membrane phospholipid phosphatidylserine (PS), which is usually enriched in the inner membrane leaflet but is aberrantly
exposed to the outer membrane leaflet upon direct contact with H.
Most of the patients with QRS tachycardia admitted to the emergency unit is ventricular tachycardia, whereas aberrantly
conducted supraventricular tachycardia is observed to a lesser extent.
These are, therefore, a class of gene expressed aberrantly
and may also undergo mutation resulting in cancers and are novel markers that may behave as oncogenes or tumour suppressor genes.
Current understanding of the functional roles of aberrantly
expressed microRNAs in esophageal cancer.