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acantholysis

   Also found in: Medical 0.01 sec.
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Noun1.acantholysis - a breakdown of a cell layer in the epidermis (as in pemphigus)acantholysis - a breakdown of a cell layer in the epidermis (as in pemphigus)
disease of the skin, skin disease, skin disorder - a disease affecting the skin
pemphigus - a skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membrane


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The histology shows acantholysis similar to that of pemphigus vulgaris, but the clinical features, because of fairly marked erythema around the blisters, simulate erythema multiforme bullosum.
Signs of the classic HSV cytopathic effect included the presence of intracellular proteinaceous fluid, ballooning degeneration of epithelial cells, and acantholysis (figure 2, A) as well as intranuclear inclusion bodies and a ground-glass appearance of some nuclei (figure 2, B).
Suprabasilar acantholysis was focally found within the epithelium of a portion of the infundibulum of the central cystic structure (Fig.
 
 
 
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