Both groups took the drug acarbose
to help control blood glucose.
The two agents is this subclass are acarbose
(Precose) and miglitol (Glyset).
The present study attempts to investigate the effect of adjunctive therapy with metformin and acarbose
in patients with Type-1 diabetes mellitus.
For those with metformin intolerance, 150–300 mg acarbose
per day (the average dose of acarbose
is 300 mg/d for persons who also need to lose weight) or thiazolidinediones (TZDs) such as 4–8 mg rosiglitazone per day or 15–45 mg pioglitazone per day are recommended.
has been widely studied for the treatment of Type 2 diabetes (Ritz et al.
All 276 patients were using various hypoglycemic agents namely, metformin, acarbose
, sulfonylureas, insulin therapy.
, Cardiovascular outcome trials, Cardiovascular Phenotype, Diabetes, Dyslipidaemia, Empagliflozin, Metformin, Obesity, Overweight.
Tuccori and his colleagues studied 145,806 patients with newly diagnosed type 2 diabetes, defined as a first-ever prescription for thiazolidinediones, metformin, sulfonylureas, prandial glucose regulators, acarbose
, dipeptidyl peptidase-4 inhibitors, glucagonlike peptide agonists, or sodium-glucose cotransporter-2 inhibitors.
Of the fractions, only the acidic cherry and apple polysaccharides demonstrated glucosidase inhibition with values comparable to those of the acarbose
et al, Comparison of maltose and acarbose
as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease.
By mid 1990, metformin became available in our country, followed by acarbose
and the thiazolinediones.
Of them, the glucosidase inhibitors such as acarbose
has been demonstrated to have beneficial effects in preventing the incidence of acidosis in steers (McLaughlin et al.