acetylcholinesterase


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Related to acetylcholinesterase: Acetylcholinesterase inhibitors

a·ce·tyl·cho·li·nes·ter·ase

 (ə-sēt′l-kō′lə-nĕs′tə-rās′, -rāz′)
n.
An enzyme in the blood and in certain tissues that catalyzes the hydrolysis of acetylcholine.

acetylcholinesterase

(əˈsiːtaɪlˌkəʊliːnˈɛstərˌeɪz; ˈæsɪtaɪl-)
n
(Biochemistry) an enzyme in nerve cells that is responsible for the destruction of acetylcholine and thus for switching off excitation of the nerve

a•ce•tyl•cho•lin•es•ter•ase

(əˌsit lˌkoʊ ləˈnɛs təˌreɪs, -ˌreɪz, əˌsɛt-, ˌæs ɪ tl-)

n.
an enzyme that counteracts the effects of acetylcholine by hydrolyzing it to choline and acetate.
[1945–50]
References in periodicals archive ?
Rowland et al have suggested guidelines for managing cardiovascular risks prior to and during treatment with acetylcholinesterase inhibitors.
The most important changes observed are a decrease in the acetylcholine neurotransmitter, as well in levels of the respective enzymes that synthesize and degrade acetylcholine, choline acetyltransferase and acetylcholinesterase (AChE) (Perry et al.
Screening for acetylcholinesterase inhibitors in cyanobacterial biomass by the enzyme inhibition method (Mahmood & Carmichael, 1987) demonstrated 26.
KEY WORDS: acetylcholinesterase, brain development, chlorpyrifos, diazinon, organophosphate insecticides, PC12 cells.
All patients must have been taking an acetylcholinesterase inhibitor for at least 120 days prior to baseline.
Recognizing the need to rapidly sense nerve-damaging chemicals that could be released into public places, David Lawrence Vigliarolo Bauer of Hunter College High School in New York City designed a device that detects compounds that stop the enzyme acetylcholinesterase from working.
They found that both green and black tea inhibited the activity of the enzyme acetylcholinesterase (AChE), which breaks down the chemical messenger, or neurotransmitter, acetylcholine.
Acetylcholinesterase (AChE) is a membrane-bound enzyme with its active side exposed at the external leaflet of the bilayer (ectoenzyme).
In vivo inhibition of acetylcholinesterase and aliesterases by the five compounds was determined for both species.
Another drug under study is galantamine, an acetylcholinesterase inhibitor.
An acetylcholinesterase inhibitor for the treatment of mild to moderate dementia of the Alzheimer's type.

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