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acridine

   Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.
ac·ri·dine  (kr-dn)
n.
A coal tar derivative, C13H9N, that has a strongly irritating odor and is used in the manufacture of dyes and synthetics.

acridine [ˈækrɪˌdiːn]
n
(Chemistry / Elements & Compounds) a colourless crystalline solid used in the manufacture of dyes. Formula: C13H9N


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Fluorescent Reagents Intercalation into dsDNA for Detection of Hybridization Intercalators, such as ethidiun bromide (EB), acridine orange (AO) and thiazole orange (TO), were selectively tethered into DNA hydrids by noncovalent bond in these DNA biosensors.
An increase of acid vesicular organelles (AVOs) detected by acridine orange staining for lysosomes as well as conversion of LC3B-I into LC3B-II by immunoblotting and an increased punctuated pattern of cytoplasmic LC3B by fluorescent immunostaining all supported induction of enhanced autophagy in response to VK2 in HL-60bcl-2 cells.
 
 
 
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