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David Hansen, President and CEO of MabVax Therapeutics, explained, "We challenged the non-human primates in this acute dose range finding study with multiple dose levels to assess drug pharmacokinetics, as well as with repeated doses of the antibody to identify any adverse toxicology signals.
Brain scans taken of people before and after an acute dose of a commonly prescribed serotonin reuptake inhibitor reveal changes in connectivity within three hours, say researchers.
According to a study conducted by scientists at Baylor University, an acute dose of alcohol may cause greater impairment in coordination, learning, and memory in the elderly than in young people.
NEM was evaluated for cytotoxicity, genotoxicity and oral toxicity (both single acute dose and 90-day repeated-dose) at doses up to 50 times the clinically tested human equivalent dose.
Possible effects of an acute dose can for all to examine the body.
The talk of racing AN ATTACK of the often excruciatingly painful shingles is no laughing matter, but Lambourn owner and syndicate supremo Henry Ponsonby was smiling away his plight because it saved him from an acute dose of embarrassment.
d) A combination of SC, ES and RR is effective in improving attention, speed and accuracy in cognitive tasks two hours after an acute dose.
The acute dose is the geometric mean of the product of the dose A that produced 100% mortality or clinical signs in one group and the dose B that produced 0% mortality in another group.
2003) reported that the body burden of arsenic in mice under repeated-dose exposure was significantly higher than that under acute exposures; moreover, elimination of arsenic after repeated doses was significantly slower than after an acute dose.
The 9/10 and 10/10 subjects experienced the significantly increased euphoria and anxiety considered typical with a low acute dose of amphetamine.
Robinson had already familiarised himself with the two-by-four room on the aircraft (toilets), as he'd boarded the plane with an acute dose of food poisoning.
And while the report's authors calculate that the odds of any single child getting an acute dose of pesticides are small, odds that a dangerous dose will reach a significant number across the whole population, 20 million U.
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