acylate

(redirected from acylating)
Also found in: Medical.

acylate

(ˈeɪsaɪˌleɪt)
vb (intr)
to introduce one or more acyl groups into a compound
References in periodicals archive ?
Due to the weak nucleophilicity of the amino group of the 2-aminothiazole and its 4-phenyl derivative by participation in resonance with the pi- system, condensation with activated acylating reagents such as chloroformates, acid chlorides and acid anhydrides provided a good strategy to prepare a number of thiazole derivatives via nucleophilic substitution reactions.
Furthermore, the aromatic amide (+)-tembamide (5), and the phenylpropanoid (+)-ailanthoidiol (6) were esterified with different acylating reagents to afford seven alkanoyi/aroyl esters (7-13).
He begins with the reagents and processes: alkylating agents, acylating agents, nitration and nitrosylation, oxidation, and modifying proteins with reducing agents.
The role of NBS is not clear in the acetylation reaction but a plausible explanation is that NBS might act as a source for Br+ which in turn activates the carbonyl groups of acetic anhydride to produce the highly reactive acylating agent (CH3-CO-N-OCCH2CH2CO-).
Like simple alcohol, the hydroxyl groups of cellulose can be esterified by reactions with acids or other acylating agents.
The most commonly used initiators for cationic polymerization are protic acids, Lewis acids, stable organic salts and alkylating or acylating covalent compounds.
A few pieces of ice was added to the reaction mixture to decompose unreacted (excess) acylating agent and extracted with dichloromethane (DCM) (3 x 5 mL).
Derouane [6,7] studied adsorption, reaction, and deactivation of zeolite H-BEA in the acetylation of anisole with acetic acid as the acylating agent.
Ceftaroline possess improved anti-MRSA activity as a result of the altered 3' side chain that interacts with an allosteric binding site on PBP2a, allowing the [beta]-lactam ring to have optimal access to the active-site serine, acylating the site and initiating the series of biochemical events that result in bacterial cell death (120).
By acylating PF resin, Miller and Rosthauser (2002) found that the esterification of phenolic oxygen greatly reduced the reactivity of the PF portion in the resin mix when combining the pMDI to form a singlephase liquid material with a storage life of more than 2 weeks at room temperature.
However, the attractiveness of this pathway is unfortunately offset by the high cost of acylating agent.
The court held that since "one cannot chose from the unknown" and "one having no knowledge of this acid could hardly find it obvious to make any cephem using this acid as an acylating agent, much less the particular cephem," the process was nonobvious.